[HTML][HTML] Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

NI Mazur, J Terstappen, R Baral, A Bardají… - The Lancet Infectious …, 2023 - thelancet.com
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged> 60 years). Efforts to develop a …

[HTML][HTML] Tackling COVID-19 with neutralizing monoclonal antibodies

D Corti, LA Purcell, G Snell, D Veesler - Cell, 2021 - cell.com
Monoclonal antibodies (mAbs) have revolutionized the treatment of several human
diseases, including cancer and autoimmunity and inflammatory conditions, and represent a …

[HTML][HTML] Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology

L Piccoli, YJ Park, MA Tortorici, N Czudnochowski… - Cell, 2020 - cell.com
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-
CoV-2 infection is crucial for understanding immune protection and identifying targets for …

[HTML][HTML] RSV prevention in all infants: which is the most preferable strategy?

S Esposito, B Abu Raya, E Baraldi, K Flanagan… - Frontiers in …, 2022 - frontiersin.org
Respiratory syncytial virus (RSV) causes a spectrum of respiratory illnesses in infants and
young children that may lead to hospitalizations and a substantial number of outpatient …

[HTML][HTML] UPDATE-2022 Italian guidelines on the management of bronchiolitis in infants

S Manti, A Staiano, L Orfeo, F Midulla… - Italian journal of …, 2023 - Springer
Bronchiolitis is an acute respiratory illness that is the leading cause of hospitalization in
young children. This document aims to update the consensus document published in 2014 …

Development of mRNA vaccines against respiratory syncytial virus (RSV)

X Qiu, S Xu, Y Lu, Z Luo, Y Yan, C Wang, J Ji - Cytokine & Growth Factor …, 2022 - Elsevier
Respiratory syncytial virus (RSV) is a single-stranded negative-sense RNA virus that is the
primary etiologic pathogen of bronchitis and pneumonia in infants and the elderly. Currently …

Palivizumab prophylaxis in infants and young children at increased risk of hospitalization for respiratory syncytial virus infection

MT Caserta, ST O'Leary, FM Munoz, SL Ralston - Pediatrics, 2023 - publications.aap.org
Guidance from the American Academy of Pediatrics (AAP) for the use of palivizumab
prophylaxis against respiratory syncytial virus (RSV) was first published in a policy statement …

[HTML][HTML] The road to approved vaccines for respiratory syncytial virus

TJ Ruckwardt - NPJ vaccines, 2023 - nature.com
After decades of work, several interventions to prevent severe respiratory syncytial virus
(RSV) disease in high-risk infant and older adult populations have finally been approved …

The journey to a respiratory syncytial virus vaccine

A Mejias, R Rodríguez-Fernández, S Oliva… - Annals of Allergy …, 2020 - Elsevier
Objective The high burden associated with respiratory syncytial virus (RSV) has made the
development of RSV vaccine (s) a global health high priority. This review summarizes the …

[HTML][HTML] Inhalation monoclonal antibody therapy: a new way to treat and manage respiratory infections

HA Parray, S Shukla, R Perween, R Khatri… - Applied microbiology …, 2021 - Springer
The route of administration of a therapeutic agent has a substantial impact on its success.
Therapeutic antibodies are usually administered systemically, either directly by intravenous …