Synapse organizing proteins are multifaceted molecules that coordinate the complex
processes of brain development and plasticity at the level of individual synapses. Their …

Protein phosphatases are major regulators of signal transduction and they are involved in
key cellular mechanisms such as proliferation, differentiation, and cell survival. Here we …

Lrfn2/SALM1 is a PSD-95-interacting synapse adhesion molecule, and human LRFN2 is
associated with learning disabilities. However its role in higher brain function and underlying …

Trans-synaptic cell-adhesion molecules are critical for governing various stages of synapse
development and specifying neural circuit properties via the formation of multifarious …

LAR-type receptor phosphotyrosine-phosphatases (LAR-RPTPs) are presynaptic adhesion
molecules that interact trans-synaptically with multitudinous postsynaptic adhesion …

Background Immune checkpoint inhibitor (ICI) therapy improves the survival of patients with
advanced bladder cancer (BLCA); however, its overall effectiveness is limited, and many …

SALM5, a synaptic adhesion molecule implicated in autism, induces presynaptic
differentiation through binding to the LAR family receptor protein tyrosine phosphatases …

The brain harbors billions of neurons that form distinct neural circuits with exquisite
specificity. Specific patterns of connectivity between distinct neuronal cell types permit the …

Leucine-rich-repeat transmembrane neuronal proteins (LRRTMs) are a family of four
synapse organizing proteins critical for the development and function of excitatory synapses …

Alternative splicing regulates trans‐synaptic adhesions and synapse development, but
supporting in vivo evidence is limited. PTP δ, a receptor tyrosine phosphatase adhering to …