Haemocyte‐mediated immunity in insects: Cells, processes and associated components in the fight against pathogens and parasites

I Eleftherianos, C Heryanto, T Bassal, W Zhang… - …, 2021 - Wiley Online Library
The host defence of insects includes a combination of cellular and humoral responses. The
cellular arm of the insect innate immune system includes mechanisms that are directly …

Drosophila as a Genetic Model for Hematopoiesis

U Banerjee, JR Girard, LM Goins, CM Spratford - Genetics, 2019 - academic.oup.com
In this FlyBook chapter, we present a survey of the current literature on the development of
the hematopoietic system in Drosophila. The Drosophila blood system consists entirely of …

Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila

B Cho, SH Yoon, D Lee, F Koranteng… - Nature …, 2020 - nature.com
The Drosophila lymph gland, the larval hematopoietic organ comprised of prohemocytes
and mature hemocytes, has been a valuable model for understanding mechanisms …

The cell-mediated immunity of Drosophila melanogaster: hemocyte lineages, immune compartments, microanatomy and regulation

V Honti, G Csordás, É Kurucz, R Márkus… - Developmental & …, 2014 - Elsevier
In the animal kingdom, innate immunity is the first line of defense against invading
pathogens. The dangers of microbial and parasitic attacks are countered by similar …

Macrophage-derived upd3 cytokine causes impaired glucose homeostasis and reduced lifespan in Drosophila fed a lipid-rich diet

KJ Woodcock, K Kierdorf, CA Pouchelon, V Vivancos… - Immunity, 2015 - cell.com
Long-term consumption of fatty foods is associated with obesity, macrophage activation and
inflammation, metabolic imbalance, and a reduced lifespan. We took advantage of …

Macrophages and cellular immunity in Drosophila melanogaster

KS Gold, K Brückner - Seminars in Immunology, 2015 - Elsevier
The invertebrate Drosophila melanogaster has been a powerful model for understanding
blood cell development and immunity. Drosophila is a holometabolous insect, which …

Extracellular adenosine mediates a systemic metabolic switch during immune response

A Bajgar, K Kucerova, L Jonatova, A Tomcala… - PLoS …, 2015 - journals.plos.org
Immune defense is energetically costly, and thus an effective response requires metabolic
adaptation of the organism to reallocate energy from storage, growth, and development …

[HTML][HTML] Interaction between differentiating cell-and niche-derived signals in hematopoietic progenitor maintenance

BC Mondal, T Mukherjee, L Mandal, CJ Evans… - Cell, 2011 - cell.com
Maintenance of a hematopoietic progenitor population requires extensive interaction with
cells within a microenvironment or niche. In the Drosophila hematopoietic organ, niche …

Spatial and temporal in vivo analysis of circulating and sessile immune cells in mosquitoes: hemocyte mitosis following infection

JG King, JF Hillyer - BMC biology, 2013 - Springer
Background Mosquitoes respond to infection by mounting immune responses. The primary
regulators of these immune responses are cells called hemocytes, which kill pathogens via …

Drosophila sessile hemocyte clusters are true hematopoietic tissues that regulate larval blood cell differentiation

AB Leitao, E Sucena - Elife, 2015 - elifesciences.org
Virtually all species of coelomate animals contain blood cells that display a division of labor
necessary for homeostasis. This functional partition depends upon the balance between …