Real-time estimation of the epidemic reproduction number: Scoping review of the applications and challenges

RK Nash, P Nouvellet, A Cori - PLOS Digital Health, 2022 - journals.plos.org
The time-varying reproduction number (Rt) is an important measure of transmissibility during
outbreaks. Estimating whether and how rapidly an outbreak is growing (Rt> 1) or declining …

How epidemics end

E Charters, K Heitman - Centaurus, 2021 - Wiley Online Library
As COVID‐19 drags on and new vaccines promise widespread immunity, the world's
attention has turned to predicting how the present pandemic will end. How do societies …

Optimizing the timing of an end-of-outbreak declaration: Ebola virus disease in the Democratic Republic of the Congo

WS Hart, JM Buckingham, M Keita… - Science …, 2024 - science.org
Following the apparent final case in an Ebola virus disease (EVD) outbreak, the decision to
declare the outbreak over must balance societal benefits of relaxing interventions against …

Using real-time modelling to inform the 2017 Ebola outbreak response in DR Congo

R Thompson, W Hart, M Keita, I Fall, A Gueye… - Nature …, 2024 - nature.com
Important policy questions during infections disease outbreaks include: i) How effective are
particular interventions?; ii) When can resource-intensive interventions be removed? We …

How mathematical modelling can inform outbreak response vaccination

M Shankar, AM Hartner, CRK Arnold, E Gayawan… - BMC Infectious …, 2024 - Springer
Mathematical models are established tools to assist in outbreak response. They help
characterise complex patterns in disease spread, simulate control options to assist public …

Early intervention is the key to success in COVID-19 control

RN Binny, MG Baker, SC Hendy… - Royal Society …, 2021 - royalsocietypublishing.org
New Zealand responded to the COVID-19 pandemic with a combination of border
restrictions and an Alert Level (AL) system that included strict stay-at-home orders. These …

Exact calculation of end-of-outbreak probabilities using contact tracing data

NV Bradbury, WS Hart… - Journal of the …, 2023 - royalsocietypublishing.org
A key challenge for public health policymakers is determining when an infectious disease
outbreak has finished. Following a period without cases, an estimate of the probability that …

Inferring the reproduction number using the renewal equation in heterogeneous epidemics

WD Green, NM Ferguson… - Journal of The Royal …, 2022 - royalsocietypublishing.org
Real-time estimation of the reproduction number has become the focus of modelling groups
around the world as the SARS-CoV-2 pandemic unfolds. One of the most widely adopted …

A modelling analysis of a new multi-stage pathway for classifying achievement of public health milestones for leprosy

EL Davis, RE Crump, GF Medley… - … of the Royal …, 2023 - royalsocietypublishing.org
Several countries have come close to eliminating leprosy, but leprosy cases continue to be
detected at low levels. Due to the long, highly variable delay from infection to detection, the …

[HTML][HTML] A hospital-related outbreak of SARS-CoV-2 associated with variant Epsilon (B. 1.429) in Taiwan: transmission potential and outbreak containment under …

AR Akhmetzhanov, S Jung, HY Cheng… - International Journal of …, 2021 - Elsevier
Objectives A hospital-related cluster of 22 cases of coronavirus disease 2019 (COVID-19)
occurred in Taiwan in January–February 2021. Rigorous control measures were introduced …