Effect of aging on homeostasis in the soft tissue of the periodontium: A narrative review

YG Kim, SM Lee, S Bae, T Park, H Kim, Y Jang… - Journal of personalized …, 2021 - mdpi.com
Aging is characterized by a progressive decline or loss of physiological functions, leading to
increased susceptibility to disease or death. Several aging hallmarks, including genomic …

New perspectives on avian models for studies of basic aging processes

JM Harper, DJ Holmes - Biomedicines, 2021 - mdpi.com
Avian models have the potential to elucidate basic cellular and molecular mechanisms
underlying the slow aging rates and exceptional longevity typical of this group of vertebrates …

Development and validation of a nomogram for the prediction of hospital mortality of patients with encephalopathy caused by microbial infection: a retrospective cohort …

L Zhao, Y Li, Y Wang, Q Gao, Z Ge, X Sun… - Frontiers in …, 2021 - frontiersin.org
Background Hospital mortality is high for patients with encephalopathy caused by microbial
infection. Microbial infections often induce sepsis. The damage to the central nervous …

Tissue-specific biological aging predicts progression in prostate cancer and acute myeloid leukemia

A Ramakrishnan, I Datta, S Panja, H Patel, Y Liu… - Frontiers in …, 2023 - frontiersin.org
Introduction Chronological aging is a well-recognized diagnostic and prognostic factor in
multiple cancer types, yet the role of biological aging in manifesting cancer progression has …

Pathogenic factors identification of brain imaging and gene in late mild cognitive impairment

X Bi, L Li, R Xu, Z Xing - Interdisciplinary Sciences: Computational Life …, 2021 - Springer
Mild cognitive impairment (MCI) is a dangerous signal of severe cognitive decline. It can be
separated into two steps: early MCI (EMCI) and late MCI (LMCI). As the post-state of MCI …

Targeted co-expression networks for the study of traits

A Gómez-Pascual, G Rocamora-Pérez, L Ibanez… - Scientific Reports, 2024 - nature.com
Abstract Weighted Gene Co-expression Network Analysis (WGCNA) is a widely used
approach for the generation of gene co-expression networks. However, networks generated …

Housekeeping protein-coding genes interrogated with tissue and individual variations

KF Tung, CY Pan, W Lin - Scientific Reports, 2024 - nature.com
Housekeeping protein-coding genes are stably expressed genes in cells and tissues that
are thought to be engaged in fundamental cellular biological functions. They are often …

Establishing a genomic radiation-age association for space exploration supplements lung disease differentiation

NA Ruprecht, S Singhal, K Schaefer, JS Gill… - Frontiers in Public …, 2023 - frontiersin.org
Purpose One possible way to quantify each individual's response or damage from ionizing
radiation is to estimate their accelerated biological age following exposure. Since there is …

Drug repositioning for SARS-CoV-2 by Gaussian kernel similarity bilinear matrix factorization

Y Wang, J Xiang, C Liu, M Tang, R Hou… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), a disease caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is currently spreading rapidly around the world …

Predicting Age from Human Lung Tissue Through Multi-modal Data Integration

A Moraes, M Moreno, R Ribeiro, PG Ferreira - International Conference on …, 2023 - Springer
The accurate prediction of biological age can bring important benefits in promoting
therapeutic and behavioural strategies for healthy aging. We propose the development of …