The nuclear factor kappa B signaling pathway is a master regulator of renal fibrosis

N Ren, WF Wang, L Zou, YL Zhao, H Miao… - Frontiers in …, 2024 - frontiersin.org
Renal fibrosis is increasingly recognized as a global public health problem. Acute kidney
injury (AKI) and chronic kidney disease (CKD) both result in renal fibrosis. Oxidative stress …

From Acute to Chronic: Unraveling the Pathophysiological Mechanisms of the Progression from Acute Kidney Injury to Acute Kidney Disease to Chronic Kidney …

TH Yeh, KC Tu, HY Wang, JY Chen - International journal of molecular …, 2024 - mdpi.com
This article provides a thorough overview of the biomarkers, pathophysiology, and molecular
pathways involved in the transition from acute kidney injury (AKI) and acute kidney disease …

Knockout of integrin αvβ6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages

C Zhu, R Zheng, X Han, Z Tang, F Li, X Hu, R Lin… - Cell Death & …, 2024 - nature.com
Integrin αvβ6 holds promise as a therapeutic target for organ fibrosis, yet targeted therapies
are hampered by concerns over inflammatory-related side effects. The role of αvβ6 in renal …

Loss of SAV1 in Kidney Proximal Tubule Induces Maladaptive Repair after Ischemia and Reperfusion Injury

D Moon, BJ Padanilam, KM Park, J Kim - International Journal of …, 2024 - mdpi.com
Kidney ischemia and reperfusion injury (IRI) is a significant contributor to acute kidney injury
(AKI), characterized by tubular injury and kidney dysfunction. Salvador family WW domain …

Glutaminolysis is a Potential Therapeutic Target for Kidney Diseases

LP Ou, YJ Liu, ST Qiu, C Yang, JX Tang… - Diabetes, Metabolic …, 2024 - Taylor & Francis
Metabolic reprogramming contributes to the progression and prognosis of various kidney
diseases. Glutamine is the most abundant free amino acid in the body and participates in …

From Acute to Chronic: Unraveling the Pathophysiological Mechanisms of Acute Kidney Injury, Acute Kidney Disease to Chronic Kidney Disease Progression

TH Yeh, KC Tu, HY Wang, JY Chen - 2024 - preprints.org
This article provides a thorough overview of biomarkers, pathophysiology, and molecular
pathways involved in the transition from acute kidney injury (AKI), acute kidney disease …