Multifunctional biomolecule nanostructures for cancer therapy

J Wang, Y Li, G Nie - Nature Reviews Materials, 2021 - nature.com
Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …

Protein assembly by design

J Zhu, N Avakyan, A Kakkis, AM Hoffnagle… - Chemical …, 2021 - ACS Publications
Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …

Biomedical applications of DNA‐based hydrogels

J Gačanin, CV Synatschke… - Advanced Functional …, 2020 - Wiley Online Library
Nucleic acids are gaining significant attention as versatile building blocks for the next
generation of soft materials. Due to significant advances in the chemical synthesis and …

[HTML][HTML] Polymer bioconjugates: Modern design concepts toward precision hybrid materials

C Chen, DYW Ng, T Weil - Progress in Polymer Science, 2020 - Elsevier
The conjugation of synthetic polymers with various biomolecules provides an easy access to
biohybrid materials which combine advantages from both the synthetic world and Nature …

[HTML][HTML] Computational methods to predict protein aggregation

S Navarro, S Ventura - Current Opinion in Structural Biology, 2022 - Elsevier
In most cases, protein aggregation stems from the establishment of non-native
intermolecular contacts. The formation of insoluble protein aggregates is associated with …

MoDAFold: a strategy for predicting the structure of missense mutant protein based on AlphaFold2 and molecular dynamics

L Zheng, S Shi, X Sun, M Lu, Y Liao… - Briefings in …, 2024 - academic.oup.com
Protein structure prediction is a longstanding issue crucial for identifying new drug targets
and providing a mechanistic understanding of protein functions. To enhance the progress in …

Metal-binding peptides and their potential to enhance the absorption and bioavailability of minerals

TJ Ashaolu, CC Lee, JO Ashaolu, H Pourjafar… - Food chemistry, 2023 - Elsevier
Minerals including calcium, iron, zinc, magnesium, and copper have several human
nutritional functions due to their metabolic activities. Body tissues require sufficient levels of …

What is holding back the development of antiviral metallodrugs? A literature overview and implications for SARS-CoV-2 therapeutics and future viral outbreaks

REF de Paiva, AM Neto, IA Santos, ACG Jardim… - Dalton …, 2020 - pubs.rsc.org
In light of the Covid-19 outbreak, this review brings together historical and current literature
efforts towards the development of antiviral metallodrugs. Classical compounds such as …

[HTML][HTML] Colloidal nanoparticles prepared from zein and casein: interactions, characterizations and emerging food applications

Y Wang, Y Luo - Food Science and Human Wellness, 2023 - Elsevier
Protein colloidal nanoparticles (NPs) are ubiquitous present in nature and function as
building blocks with multiple functions in both food formulations and biological processes …

Protein assemblies: nature-inspired and designed nanostructures

IW Hamley - Biomacromolecules, 2019 - ACS Publications
Ordered protein assemblies are attracting interest as next-generation biomaterials with a
remarkable range of structural and functional properties, leading to potential applications in …