Elastin-like polypeptides as building motifs toward designing functional nanobiomaterials

DHT Le, A Sugawara-Narutaki - Molecular Systems Design & …, 2019 - pubs.rsc.org
Taking inspiration from naturally-occurring proteins, scientists have created protein polymers
consisting of functional amino acid sequences that have evolved in nature. The functions of …

[HTML][HTML] Self-assembly in elastin-like recombinamers: a mechanism to mimic natural complexity

L Quintanilla-Sierra, C García-Arévalo… - Materials Today Bio, 2019 - Elsevier
The topic of self-assembled structures based on elastin-like recombinamers (ELRs, ie,
elastin-like polymers recombinantly bio-produced) has released a noticeable amount of …

Trends in the development of tailored elastin-like recombinamer–Based porous biomaterials for soft and hard tissue applications

L Mbundi, M Gonzalez-Perez, F Gonzalez-Perez… - Frontiers in …, 2021 - frontiersin.org
Porous biomaterials are of significant interest in a variety of biomedical applications as they
enable the diffusion of nutrients and gases as well as the removal of metabolic waste from …

Fibrous scaffolds from elastin-based materials

JC Rodriguez-Cabello, I Gonzalez De Torre… - … in Bioengineering and …, 2021 - frontiersin.org
Current cutting-edge strategies in biomaterials science are focused on mimicking the design
of natural systems which, over millions of years, have evolved to exhibit extraordinary …

Thixotropic hydrogels composed of self-assembled nanofibers of double-hydrophobic elastin-like block polypeptides

Y Sugioka, J Nakamura, C Ohtsuki… - International Journal of …, 2021 - mdpi.com
Physically crosslinked hydrogels with thixotropic properties attract considerable attention in
the biomedical research field because their self-healing nature is useful in cell …

Intrafibrillar mineralization of self-assembled elastin-like recombinamer fibrils

Y Li, JC Rodriguez-Cabello… - ACS Applied Materials & …, 2017 - ACS Publications
Biomineralization of bone, a controlled process where hydroxyapatite nanocrystals
preferentially deposit in collagen fibrils, is achieved by the interplay of the collagen matrix …

Characteristics of collagen-rich extracellular matrix hydrogels and their functionalization with poly (ethylene glycol) derivatives for enhanced biomedical applications: a …

M Rangel-Argote, JA Claudio-Rizo… - ACS Applied Bio …, 2018 - ACS Publications
The hydrogels of natural extracellular matrix (ECM) are excellent biomaterials with
promising applications in the physiological manufacture of three-dimensional (3D) …

Complex morphogenesis by a model intrinsically disordered protein

C González‐Obeso, M González‐Pérez, JF Mano… - Small, 2020 - Wiley Online Library
The development of intricate and complex self‐assembling structures in the micrometer
range, such as biomorphs, is a major challenge in materials science. Although complex …

Charge density as a molecular modulator of nanostructuration in intrinsically disordered protein polymers

S Acosta, L Poocza, L Quintanilla-Sierra… - …, 2020 - ACS Publications
Intrinsically disordered protein polymers (IDPPs) have attracted a lot of attention in the
development of bioengineered devices and for use as study models in molecular biology …

Tailoring the formation and stability of self-assembled structures from precisely engineered intrinsically disordered protein polymers: A comprehensive review

FT Doole, CP Camp, M Kim - Giant, 2023 - Elsevier
Intrinsically disordered proteins (IDPs) are a class of proteins that lack stable three-
dimensional structures. Despite their natural tendency to be disordered, precise modulations …