Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …

These guidelines will be updated every four years. Vascular centres are encouraged to audit
implementations made as a result of the guidelines. Audit cycles should be repeated and …

The incidence of dementia and cardiovascular disease (CVD) increases with age. Current
evidence supports the role for both atherosclerosis and arteriosclerosis as a common …

Microglial activation participates in white matter injury after cerebral hypoperfusion.
However, the underlying mechanism is unclear. Here, we explore whether activated …

Atherosclerosis is the focal expression of a systemic disease affecting medium‐and large‐
sized arteries, in which traditional cardiovascular risk factor and immune factors play a key …

Neurons have been long regarded as the basic functional cells of the brain, whereas
astrocytes and microglia only as elements of support. However, proper intercommunication …

Sarcopenia characterized by reduced skeletal muscle mass and decreased muscle strength
is increasing in prevalence globally. The pathophysiology of sarcopenia is related to various …

Dementia is growing at an alarming rate worldwide. Although Alzheimer disease is the
leading cause, over 50% of individuals diagnosed with Alzheimer disease have vascular …

A substantial body of evidence supports the hypothesis of a vascular component in the
pathogenesis of Alzheimer's disease (AD). Cerebral hypoperfusion and blood-brain barrier …