Fear extinction in the human brain: A meta-analysis of fMRI studies in healthy participants
The study of fear extinction represents an important example of translational neuroscience in
psychiatry and promises to improve the understanding and treatment of anxiety and fear …
psychiatry and promises to improve the understanding and treatment of anxiety and fear …
Noradrenergic modulation of fear conditioning and extinction
TF Giustino, S Maren - Frontiers in behavioral neuroscience, 2018 - frontiersin.org
The locus coeruleus norepinephrine (LC-NE) system plays a broad role in learning and
memory. Here we begin with an overview of the LC-NE system. We then consider how both …
memory. Here we begin with an overview of the LC-NE system. We then consider how both …
Why we need nonhuman primates to study the role of ventromedial prefrontal cortex in the regulation of threat-and reward-elicited responses
AC Roberts, HF Clarke - Proceedings of the National …, 2019 - National Acad Sciences
The ventromedial prefrontal cortex (vmPFC) is consistently implicated in the cognitive and
emotional symptoms of many psychiatric disorders, but the causal mechanisms of its …
emotional symptoms of many psychiatric disorders, but the causal mechanisms of its …
Know thy SEFL: Fear sensitization and its relevance to stressor-related disorders
Extreme stress can cause long-lasting changes in affective behavior manifesting in
conditions such as post-traumatic stress disorder (PTSD). Understanding the biological …
conditions such as post-traumatic stress disorder (PTSD). Understanding the biological …
[HTML][HTML] Maturation of amygdala inputs regulate shifts in social and fear behaviors: a substrate for developmental effects of stress
Stress can negatively impact brain function and behaviors across the lifespan. However,
stressors during adolescence have particularly harmful effects on brain maturation, and on …
stressors during adolescence have particularly harmful effects on brain maturation, and on …
Physical activity and exercise as a tool to cure anxiety and posttraumatic stress disorder
S Sabri, N Rashid, ZX Mao - Mental Illness, 2023 - Wiley Online Library
Anxiety and posttraumatic stress disorder (PTSD) are the most prevalent psychiatric
conditions and significant public health problems. However, research has tended to support …
conditions and significant public health problems. However, research has tended to support …
[HTML][HTML] Impact of stress resilience and susceptibility on fear learning, anxiety, and alcohol intake
ST Gonzalez, V Marty, I Spigelman, SP Reise… - Neurobiology of …, 2021 - Elsevier
Post-traumatic stress disorder (PTSD) can develop after exposure to traumatic events and
severely impacts the quality of life. PTSD is frequently comorbid with substance use …
severely impacts the quality of life. PTSD is frequently comorbid with substance use …
Dissociation in effective treatment and behavioral phenotype between stress-enhanced fear learning and learned helplessness
MA Conoscenti, MS Fanselow - Frontiers in behavioral neuroscience, 2019 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a debilitating disease with relatively high lifetime
prevalence. It is marked by a high diversity of symptoms and comorbidity with other …
prevalence. It is marked by a high diversity of symptoms and comorbidity with other …
Mixed selectivity encoding and action selection in the prefrontal cortex during threat assessment
IS Grunfeld, E Likhtik - Current opinion in neurobiology, 2018 - Elsevier
Highlights•The medial prefrontal cortex uses mixed selectivity to encode emotional
stimuli.•PL and IL show action selection for conditioned motor inhibition and excitation.•BLA …
stimuli.•PL and IL show action selection for conditioned motor inhibition and excitation.•BLA …
Neural correlates of context-dependent extinction recall in social anxiety disorder: relevance of intrusions in response to aversive social experiences
S Fricke, RJ Seinsche, MK Neudert, A Schäfer… - Psychological …, 2024 - cambridge.org
BackgroundThere are phenomenological similarities between social anxiety disorder (SAD)
and posttraumatic stress disorder, such as a provoking aversive event, posttraumatic stress …
and posttraumatic stress disorder, such as a provoking aversive event, posttraumatic stress …