Coenzyme Q (CoQ) is a remarkably hydrophobic, redox-active lipid that empowers diverse
cellular processes. Although most known for shuttling electrons between mitochondrial …

Stem cells persist throughout the lifespan to repair and regenerate tissues due to their
unique ability to self-renew and differentiate. Here we reflect on the recent discoveries in …

Background. Mitochondria are the energy factories of cells. The abnormality of mitochondrial
energy metabolism pathways is closely related to the occurrence and development of lung …

Metabolic requirements vary during development, and our understanding of how metabolic
activity influences cell specialization is incomplete. Here, we describe a switch from …

Cellular respiration is the prerequisite for cell survival and functions, and mitochondrial
function and microcirculation oxygen supply are essential for cellular respiration. However …

Electron transport chain (ETC) dysfunction is a common feature of mitochondrial diseases
and induces severe cellular stresses, including mitochondrial membrane potential (Δψm) …

Abstract β‐thalassemia is a disorder characterized by anemia, ineffective erythropoiesis (IE),
and iron overload, whose treatment still requires improvement. The activin receptor‐ligand …

TRIM33 is a chromatin reader required for mammalian mesendoderm differentiation after
activation of Nodal signaling, while its role in mESCs is still elusive. Here, we report that …

Cox17 is required in the assembly of mitochondrial intermembrane space (IMS) and Cu
metallization of cytochrome C oxidase (CcO) in mitochondria as well as Cu homeostasis in …

Erythroid cells undergo a highly complex maturation process, resulting in dynamic changes
that generate red blood cells (RBCs) highly rich in haemoglobin. The end stages of the …