Electron paramagnetic resonance (EPR) spectroscopy is a very powerful biophysical tool
that can provide valuable structural and dynamic information about a wide variety of …

The human KCNE gene family comprises five genes encoding single transmembrane-
spanning ion channel regulatory subunits. The primary function of KCNE subunits appears …

Pulsed EPR DEER structural studies of membrane proteins in a lipid bilayer have often been
hindered by difficulties in extracting accurate distances when compared to those of globular …

Native lipid bilayer mimetics, including those that use amphiphilic polymers, are important
for the effective study of membrane-bound peptides and proteins. Copolymers of vinyl ether …

Members of the KCNE family are accessory subunits that modulate voltage-gated potassium
channels. One member, KCNE4, has been shown to inhibit the potassium ion current in …

Membrane protein spectroscopic studies are challenging due to the difficulty introduced in
preparing homogenous and functional hydrophobic proteins incorporated into a lipid bilayer …

Styrene–maleic acid copolymers have received significant attention because of their ability
to interact with lipid bilayers and form styrene–maleic acid copolymer lipid nanoparticles …

Biological membranes are essential in providing the stability of membrane proteins in a
functional state. Functionally stable homogeneous sample is required for biophysical …

KCNE1 is a single-transmembrane protein of the KCNE family that modulates the function of
voltage-gated potassium channels, including KCNQ1. Hereditary mutations in KCNE1 have …

Lipoprotein signal peptidase (LspA) is a key enzyme in the lipoprotein processing pathway
and is responsible for cleaving the signal sequence of prolipoproteins. LspA is a membrane …