The progress in understanding and treatment of diabetic retinopathy

AW Stitt, TM Curtis, M Chen, RJ Medina… - Progress in retinal and …, 2016 - Elsevier
Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …

[HTML][HTML] Deep learning for diabetic retinopathy detection and classification based on fundus images: A review

N Tsiknakis, D Theodoropoulos, G Manikis… - Computers in biology …, 2021 - Elsevier
Diabetic Retinopathy is a retina disease caused by diabetes mellitus and it is the leading
cause of blindness globally. Early detection and treatment are necessary in order to delay or …

Diabetic retinopathy and diabetic macular oedema pathways and management: UK Consensus Working Group

WM Amoaku, F Ghanchi, C Bailey, S Banerjee… - Eye, 2020 - nature.com
The management of diabetic retinopathy (DR) has evolved considerably over the past
decade, with the availability of new technologies (diagnostic and therapeutic). As such, the …

Retinal cell damage in diabetic retinopathy

J Zhou, B Chen - Cells, 2023 - mdpi.com
Diabetic retinopathy (DR), the most common microvascular complication that occurs in
diabetes mellitus (DM), is the leading cause of vision loss in working-age adults. The …

Oxidative stress and vascular dysfunction in the retina: Therapeutic strategies

Y Ruan, S Jiang, A Musayeva, A Gericke - Antioxidants, 2020 - mdpi.com
Many retinal diseases, such as diabetic retinopathy, glaucoma, and age-related macular
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …

Oxidative stress as the main target in diabetic retinopathy pathophysiology

OM Cecilia, CG José Alberto, NP José… - Journal of diabetes …, 2019 - Wiley Online Library
Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus
(DM) causing vision impairment even at young ages. There are numerous mechanisms …

Cell–matrix interactions in the eye: From cornea to choroid

AE Pouw, MA Greiner, RG Coussa, C Jiao, IC Han… - Cells, 2021 - mdpi.com
The extracellular matrix (ECM) plays a crucial role in all parts of the eye, from maintaining
clarity and hydration of the cornea and vitreous to regulating angiogenesis, intraocular …

Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models

K Song, X Yang, G An, X Xia, J Zhao, X Xu… - Nature …, 2022 - nature.com
Type 2 diabetes mellitus is one of the most prevalent metabolic diseases presenting with
systemic pathologies, including reproductive disorders in male diabetic patients. However …

Barriers to and enablers of diabetic retinopathy screening attendance: a systematic review of published and grey literature

E Graham‐Rowe, F Lorencatto… - Diabetic …, 2018 - Wiley Online Library
Aims To identify and synthesize studies reporting modifiable barriers/enablers associated
with retinopathy screening attendance in people with Type 1 or Type 2 diabetes, and to …

From oxidative stress to inflammation in the posterior ocular diseases: diagnosis and treatment

A Dammak, F Huete-Toral, C Carpena-Torres… - Pharmaceutics, 2021 - mdpi.com
Most irreversible blindness observed with glaucoma and retina-related ocular diseases,
including age-related macular degeneration and diabetic retinopathy, have their origin in the …