Overview, consequences, and strategies for overcoming matrix effects in LC-MS analysis: a critical review

A Nasiri, R Jahani, S Mokhtari, H Yazdanpanah… - Analyst, 2021 - pubs.rsc.org
The high-performance liquid chromatography-mass spectrometry (LC-MS) technique is
widely applied to routine analysis in many matrices. Despite the enormous application of …

LC-MS application for therapeutic drug monitoring in alternative matrices

V Avataneo, A D'Avolio, J Cusato, M Cantù… - … of pharmaceutical and …, 2019 - Elsevier
Nowadays the practice of therapeutic drug monitoring, consisting in the measurement of
drugs concentrations in biological matrices in order to guide possible posological …

Development and validation of a UHPLC-MS/MS method for quantification of the prodrug remdesivir and its metabolite GS-441524: a tool for clinical pharmacokinetics …

V Avataneo, A de Nicolo, J Cusato… - Journal of …, 2020 - academic.oup.com
Background Remdesivir has received significant attention for its potential application in the
treatment of COVID-19, caused by SARS-CoV-2. Remdesivir has already been tested for …

QuEChERS LC–MS/MS screening method for mycotoxin detection in cereal products and spices

L Pantano, L La Scala, F Olibrio, FG Galluzzo… - International Journal of …, 2021 - mdpi.com
We developed and validated a screening method for mycotoxin analysis in cereal products
and spices. Ultra-high-performance liquid chromatography coupled with tandem mass …

Volumetric absorptive microsampling: a new sampling tool for therapeutic drug monitoring of antiepileptic drugs

A D'Urso, J Rudge, PN Patsalos… - Therapeutic Drug …, 2019 - journals.lww.com
Background: Volumetric absorptive microsampling (VAMS) is a novel sampling technique for
the collection of fixed-volume capillary blood. In this study, a new analytical method was …

Barriers and opportunities for the clinical implementation of therapeutic drug monitoring in oncology

BD Menz, SL Stocker, N Verougstraete… - British Journal of …, 2021 - Wiley Online Library
There are few fields of medicine in which the individualisation of medicines is more
important than in the area of oncology. Under‐dosing can have significant ramifications due …

In-syringe cotton fiber-supported liquid extraction coupled with gas chromatography-tandem mass spectrometry for the determination of free 3-mono-chloropropane-1 …

D Chen, MY Zhang, XM Bu, B Wang, XL Xu… - … of Chromatography A, 2022 - Elsevier
In the current study, natural cotton fiber was served as the supporter of water, and the water
acted as an extractant for liquid-phase microextraction of polar components in low-polar …

Direct analysis of marine dissolved organic matter using LC-FT-ICR MS

OJ Lechtenfeld, J Kaesler, EK Jennings… - … Science & Technology, 2024 - ACS Publications
Marine dissolved organic matter (DOM) is an important component of the global carbon
cycle, yet its intricate composition and the sea salt matrix pose major challenges for …

Effective mobility as a robust criterion for compound annotation and identification in metabolomics: Toward a mobility-based library

N Drouin, J Pezzatti, Y Gagnebin, V González-Ruiz… - Analytica chimica …, 2018 - Elsevier
Capillary electrophoresis (CE) presents many advantageous features as an analytical
technique in metabolomics, such as very low consumption of a sample or the possibility to …

Current state of bioanalytical chromatography in clinical analysis

HK Vlčková, V Pilařová, P Svobodová, J Plíšek, F Švec… - Analyst, 2018 - pubs.rsc.org
Chromatographic methods have become popular in clinical analysis in both routine and
research laboratories. The purpose of this review article is to provide an overview of the …