Cardiac fibrosis in patients with atrial fibrillation: mechanisms and clinical implications

MS Dzeshka, GYH Lip, V Snezhitskiy… - Journal of the American …, 2015 - jacc.org
Atrial fibrillation (AF) is associated with structural, electrical, and contractile remodeling of
the atria. Development and progression of atrial fibrosis is the hallmark of structural …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4

J Xiao, Y Pan, XH Li, XY Yang, YL Feng, HH Tan… - Cell death & …, 2016 - nature.com
Cardiac progenitor cells derived from adult heart have emerged as one of the most
promising stem cell types for cardiac protection and repair. Exosomes are known to mediate …

Biological functions of microRNAs: a review

Y Huang, XJ Shen, Q Zou, SP Wang, SM Tang… - Journal of physiology …, 2011 - Springer
MicroRNAs (miRNAs) are a recently discovered family of endogenous, noncoding RNA
molecules approximately 22 nt in length. miRNAs modulate gene expression post …

MicroRNAs as potential signatures of environmental exposure or effect: a systematic review

K Vrijens, V Bollati, TS Nawrot - Environmental health …, 2015 - ehp.niehs.nih.gov
Background: The exposome encompasses all life-course environmental exposures from the
prenatal period onward that influence health. MicroRNAs (miRNAs) are interesting entities …

MicroRNAs add a new dimension to cardiovascular disease

EM Small, RJA Frost, EN Olson - Circulation, 2010 - Am Heart Assoc
Cardiovascular disease is the predominant cause of human morbidity and mortality in
developed countries. Thus, extraordinary effort has been devoted to determining the …

Smartphone fluorescence spectroscopy

H Yu, Y Tan, BT Cunningham - Analytical chemistry, 2014 - ACS Publications
We demonstrate the first use of smartphone spectrophotometry for readout of fluorescence-
based biological assays. We evaluated the smartphone fluorimeter in the context of a …

Exosomal miR-21a-5p mediates cardioprotection by mesenchymal stem cells

KM Luther, L Haar, M McGuinness, Y Wang… - Journal of molecular and …, 2018 - Elsevier
Though experimental, stem cell transplantation has the potential to improve the condition of
the heart after myocardial infarction. It does so by reducing infarct size and inducing repair of …

MicroRNA-21 in cardiovascular disease

Y Cheng, C Zhang - Journal of cardiovascular translational research, 2010 - Springer
Abstract MicroRNA-21 (miR-21) is a highly expressed microRNA (miRNA) in cardiovascular
system. Recent studies have revealed that its expression is deregulated in heart and …

MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction

S Dong, Y Cheng, J Yang, J Li, X Liu, X Wang… - Journal of Biological …, 2009 - ASBMB
Several recent reports have suggested that microRNAs (miRNAs) might play critical roles in
acute myocardial infarction (AMI). However, the miRNA expression signature in the early …