Severe congenital neutropenias are a heterogeneous group of rare haematological
diseases characterized by impaired maturation of neutrophil granulocytes. Patients with …

Chemokines have fundamental roles in regulating immune and inflammatory responses,
primarily through their control of leukocyte migration and localization. The biological …

This review focuses on the classification, diagnosis and natural history of congenital
neutropenia (CN). CN encompasses a number of genetic disorders with chronic neutropenia …

The term congenital neutropenia encompasses a family of neutropenic disorders, both
permanent and intermittent, severe (< 0.5 G/l) or mild (between 0.5-1.5 G/l), which may also …

Neutropenia is defined as the reduction in the absolute number of neutrophils in the blood
circulation. Acute neutropenia is a relatively frequent finding, whereas disorders of …

Background: Thiopurines are an important class of immunosuppressants despite their risk
for hematopoietic toxicity and narrow therapeutic indices. Benign neutropenia related to an …

Normal neutrophil counts in peripheral blood typically range between 1500 to 8500 cells/mL
after the age of 1 year, 1 although they vary among individuals from different parts of the …

Body mass index (BMI), the prevalent indicator of obesity, is not easily grasped by patients
nor physicians. Waist circumference (WC) is correlated to obesity, is better understood and …

Recent work suggests that leukocyte telomere length (LTL), a marker of cellular aging, is
sensitive to effects of social stress and may also provide early indication of premature aging …

Aims Neutrophils play a pivotal in immunity and inflammation. We aim to investigate the
prevalence of neutropenia in the United States. Methods In this cross-sectional study …