There is increased interest in developing markers reflecting microstructural changes that
could serve as outcome measures in clinical trials. This is especially important after …

Alzheimer's Disease (AD) is characterized by structural and functional dysfunction involving
the Default Mode Network (DMN), for which the Precuneus (PC) is a key node. We proposed …

Neuroimaging biomarkers have shown high potential to map the disease processes in the
application to neurodegenerative diseases (NDD), eg, diffusion tensor imaging (DTI). For …

Background There has been increasing interest in cortical microstructure as a
complementary and earlier measure of neurodegeneration than macrostructural atrophy, but …

Objective Multimodal imaging techniques have furthered our understanding of how different
aspects of Alzheimer's disease (AD) pathology relate to one another. Diffusion tensor …

Some evidence suggests a biphasic pattern of changes in cortical thickness wherein higher,
rather than lower, thickness is associated with very early Alzheimer's disease (AD) …

Background Cortical and subcortical microstructural modifications are critical to
understanding the pathogenic changes in frontotemporal lobar degeneration (FTLD) …

Androgen deprivation therapy (ADT) has been associated with adverse effects on the brain.
ADT leads to altered testosterone levels that may affect brain morphology as well as …

The human experience is significantly impacted by timing as it structures how information is
processed. Nevertheless, the neurological foundation of time perception remains largely …

Background: Alzheimer's disease (AD) is a brain disorder characterized by atrophy of
cerebral cortex and neurofibrillary tangles. Accurate identification of individuals at high risk …