Controlled human malaria infection (CHMI) entails deliberate infection with malaria
parasites either by mosquito bite or by direct injection of sporozoites or parasitized …

Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …

Malaria in Peru, dominated by Plasmodium vivax, remains a public health problem. The
1990s saw newly epidemic malaria emerge, primarily in the Loreto Department in the …

Background The use of molecular techniques has put in the spotlight the existence of a large
mass of malaria sub-microscopic infections among apparently healthy populations. These …

Identifying molecular predictors and mechanisms of malaria disease is important for
understanding how Plasmodium falciparum malaria is controlled. Transcriptomic studies in …

Controlled human malaria infection (CHMI) provides a highly informative means to
investigate host-pathogen interactions and enable in vivo proof-of-concept efficacy testing of …

Abstract Background Malaria transmission in Latin America is generally hypoendemic and
unstable, with Plasmodium vivax as the most prevalent species. However, only a few studies …

Introduction Plasmodium vivax causes significant public health problems in endemic
regions. A vaccine to prevent disease is critical, considering the rapid spread of drug …

Almost invariably, humans become ill during primary infections with malaria parasites which
is a pathology associated with oxidative stress and perturbations in metabolism. Importantly …

Modern controlled human malaria infection (CHMI) clinical trials have almost entirely
focussed on Plasmodium falciparum, providing a highly informative means to investigate …