The functional versatility of Wnt/β-catenin signaling can be seen by its ability to act in stem
cells of the embryo and of the adult as well as in cancer stem cells. During embryogenesis …

Abstract Development of the vertebrate nervous system begins with the acquisition of neural
identity from the midline dorsal‐ectodermal cells of the gastrulating embryos. The …

Activating mutations in the gene encoding β-catenin have been identified in the paediatric
form of human craniopharyngioma (adamantinomatous craniopharyngioma, ACP), a …

Glioblastoma multiforme (GBM) is a heterogeneous disease despite its seemingly uniform
pathology. Deconvolution of The Cancer Genome Atlas's GBM gene expression data has …

Pancreatic ductal adenocarcinoma (PDAC), one of the most aggressive human
malignancies, is thought to be initiated by KRAS activation. Here we find that transcriptional …

This review addresses our current understanding of the regulatory mechanism by which N-
cadherin, a classical cadherin, affects neural progenitor cells (NPCs) during development. N …

Neurons of the dorsal hindbrain and spinal cord are central in receiving, processing and
relaying sensory perception and participate in the coordination of sensory-motor output …

Abstract The hedgehog (Hh)/glioma-associated oncogene (GLI) signaling network is among
the most important and fascinating signal transduction systems that provide critical functions …

The different modes of stem cell division are tightly regulated to balance growth and
differentiation during organ development and homeostasis, and these regulatory processes …

The primary cilium is a nonmotile microtubule‐based structure, which functions as an
antenna‐like cellular sensing organelle. The primary cilium is assembled from the basal …