Programmed cell death (PCD) pathways, including apoptosis and regulated necrosis, are
required for normal cell turnover and tissue homeostasis. Mis-regulation of PCD is …

A common need for microbial cells is the ability to respond to potentially toxic environmental
insults. Here we review the progress in understanding the response of the yeast …

Programmed cell death is a basic cellular mechanism. Apoptotic-like programmed cell death
(called apoptosis in animals) occurs in both unicellular and multicellular eukaryotes, and …

Elucidating the biology of yeast in its full complexity has major implications for science,
medicine and industry. One of the most critical processes determining yeast life and …

A cell's decision to die is controlled by a sophisticated network whose deregulation
contributes to the pathogenesis of multiple diseases including neoplastic and …

Recent results have identified a diversity of small RNAs in a wide range of organisms. In this
work, we demonstrate that Saccharomyces cerevisiae contains a small RNA population …

Yeasts, such as Saccharomyces cerevisiae, have long served as useful models for the study
of oxidative stress, an event associated with cell death and severe human pathologies. This …

Apoptosis-inducing factor (AIF) is a flavin adenine dinucleotide-containing, NADH-
dependent oxidoreductase residing in the mitochondrial intermembrane space whose …

Caspase activation has been frequently viewed as synonymous with apoptotic cell death;
however, caspases can also contribute to processes that do not culminate in cell demise …

Apoptosis‐inducing factor (AIF) is a mitochondrial flavoprotein that, after apoptosis induction,
translocates to the nucleus where it participates in apoptotic chromatinolysis. Here, we show …