Novel molecular targets participating in myocardial ischemia‐reperfusion injury and cardioprotection

NB Liu, M Wu, C Chen, M Fujino… - Cardiology research …, 2019 - Wiley Online Library
Worldwide morbidity and mortality from acute myocardial infarction (AMI) and related heart
failure remain high. While effective early reperfusion of the criminal coronary artery after a …

Exosomes: cell-free therapy for cardiovascular diseases

N He, Y Zhang, S Zhang, D Wang, H Ye - Journal of cardiovascular …, 2020 - Springer
Cardiovascular diseases (CVDs) are an important cause of death and disease worldwide.
Because injured cardiac tissue cannot be repaired itself, it is urgent to develop other …

Targeting the endothelium to achieve cardioprotection

N Herrera-Zelada, U Zuñiga-Cuevas… - Frontiers in …, 2021 - frontiersin.org
Despite considerable improvements in the treatment of myocardial infarction, it is still a
highly prevalent disease worldwide. Novel therapeutic strategies to limit infarct size are …

Progress of mesenchymal stem cell-derived exosomes in tissue repair

G Zhao, Y Ge, C Zhang, L Zhang, J Xu… - Current …, 2020 - ingentaconnect.com
Mesenchymal stem cells (MSCs) are a kind of adult stem cells with self-replication and
multidirectional differentiation, which can differentiate into tissue-specific cells under …

[HTML][HTML] Interplay between exosomes and autophagy in cardiovascular diseases: novel promising target for diagnostic and therapeutic application

J Tian, MS Popal, Y Zhao, Y Liu, K Chen… - Aging and disease, 2019 - ncbi.nlm.nih.gov
Exosome, is identified as a nature nanocarrier and intercellular messenger that regulates
cell to cell communication. Autophagy is critical in maintenance of protein homeostasis by …

Could Mesenchymal stem cell-derived exosomes be a therapeutic option for critically ill COVID-19 patients?

C Gardin, L Ferroni, JC Chachques… - Journal of Clinical …, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a pandemic viral disease originated in Wuhan,
China, in December 2019, caused by the severe acute respiratory syndrome coronavirus 2 …

Neuregulin-1 compensates for endothelial nitric oxide synthase deficiency

H Shakeri, JRA Boen, S De Moudt… - American Journal …, 2021 - journals.physiology.org
Endothelial cells (ECs) secrete different paracrine signals that modulate the function of
adjacent cells; two examples of these paracrine signals are nitric oxide (NO) and neuregulin …

How to stimulate myocardial regeneration in adult mammalian heart: existing views and new approaches

G Belostotskaya, M Hendrikx… - BioMed Research …, 2020 - Wiley Online Library
Stem cell‐based therapy has been considered as a promising option in the treatment of
ischemic heart disease. Although stem cell administration resulted in the temporary …

Exosomes: outlook for future cell-free cardiovascular disease therapy

B Barani, S Rajasingh, J Rajasingh - Exosomes in cardiovascular diseases …, 2017 - Springer
Cardiovascular diseases are the number one cause of death globally with an estimated 7.4
million people dying from coronary heart disease. Studies have been conducted to identify …

Survival differences of patients with ureteral versus pelvicalyceal tumours: a systematic review and meta-analysis

K Kaczmarek, A Lemiński, A Gołąb… - Archives of Medical …, 2019 - pmc.ncbi.nlm.nih.gov
Introduction Worse survival in upper tract urothelial carcinoma (UTUC) in the presence of a
tumour in the ureter vs. pelvicalyceal tumours is reported in some studies; however, the …