[HTML][HTML] Human trials exploring anti-aging medicines

L Guarente, DA Sinclair, G Kroemer - Cell Metabolism, 2024 - cell.com
Here, we summarize the current knowledge on eight promising drugs and natural
compounds that have been tested in the clinic: metformin, NAD+ precursors, glucagon-like …

The role of the anabolic properties of plant-versus animal-based protein sources in supporting muscle mass maintenance: a critical review

I Berrazaga, V Micard, M Gueugneau, S Walrand - Nutrients, 2019 - mdpi.com
Plant-sourced proteins offer environmental and health benefits, and research increasingly
includes them in study formulas. However, plant-based proteins have less of an anabolic …

Protein content and amino acid composition of commercially available plant-based protein isolates

SHM Gorissen, JJR Crombag, JMG Senden… - Amino acids, 2018 - Springer
The postprandial rise in essential amino acid (EAA) concentrations modulates the increase
in muscle protein synthesis rates after protein ingestion. The EAA content and AA …

The anabolic response to plant-based protein ingestion

PJM Pinckaers, J Trommelen, T Snijders… - Sports Medicine, 2021 - Springer
There is a global trend of an increased interest in plant-based diets. This includes an
increase in the consumption of plant-based proteins at the expense of animal-based …

[HTML][HTML] Higher muscle protein synthesis rates following ingestion of an omnivorous meal compared with an isocaloric and isonitrogenous vegan meal in healthy …

PJM Pinckaers, J Domić, HL Petrick, AM Holwerda… - The Journal of …, 2024 - Elsevier
Background Plant-derived proteins are considered to have fewer anabolic properties when
compared with animal-derived proteins. The anabolic properties of isolated proteins do not …

Characterising the muscle anabolic potential of dairy, meat and plant-based protein sources in older adults

SHM Gorissen, OC Witard - Proceedings of the Nutrition Society, 2018 - cambridge.org
The age-related loss of skeletal muscle mass and function is caused, at least in part, by a
reduced muscle protein synthetic response to protein ingestion. The magnitude and duration …

[HTML][HTML] Sarcopenia: Current treatments and new regenerative therapeutic approaches

JH Lo, T Yiu, MT Ong, WY Lee - Journal of orthopaedic translation, 2020 - Elsevier
Sarcopenia is characterized by loss of muscle and reduction in muscle strength that
contributes to higher mortality rate and increased incidence of fall and hospitalization in the …

Effect of soy protein supplementation on muscle adaptations, metabolic and antioxidant status, hormonal response, and exercise performance of active individuals …

R Zare, A Devrim-Lanpir, S Guazzotti, A Ali Redha… - Sports Medicine, 2023 - Springer
Background Protein supplements are important to maintain optimum health and physical
performance, particularly in athletes and active individuals to repair and rebuild their skeletal …

Evaluating the leucine trigger hypothesis to explain the post-prandial regulation of muscle protein synthesis in young and older adults: a systematic review

G Zaromskyte, K Prokopidis, T Ioannidis… - Frontiers in …, 2021 - frontiersin.org
Background: The “leucine trigger” hypothesis was originally conceived to explain the post-
prandial regulation of muscle protein synthesis (MPS). This hypothesis implicates the …

Ingestion of mycoprotein, pea protein, and their blend support comparable postexercise myofibrillar protein synthesis rates in resistance-trained individuals

S West, AJ Monteyne, G Whelehan… - American Journal …, 2023 - journals.physiology.org
Pea protein is an attractive nonanimal-derived protein source to support dietary protein
requirements. However, although high in leucine, a low methionine content has been …