Late gastrointestinal toxicity after radiotherapy for rectal cancer: a systematic review

A Sipaviciute, E Sileika, A Burneckis… - International Journal of …, 2020 - Springer
Purpose Although the multimodal cancer treatment techniques have greatly improved over
the years, irradiation-induced late gastrointestinal toxicity remains a great concern as it may …

Geriatric Radiation Oncology: What We Know and What Can We Do Better?

F Roeder, AD Jensen, K Lindel, M Mattke… - … Interventions in Aging, 2023 - Taylor & Francis
Elderly patients represent a growing subgroup of cancer patients for whom the role of
radiation therapy is poorly defined. Older patients are still clearly underrepresented in …

Decision-making strategy for rectal cancer management using radiation therapy for elderly or comorbid patients

SJ Wang, L Hathout, U Malhotra… - International Journal of …, 2018 - Elsevier
Rectal cancer predominantly affects patients older than 70 years, with peak incidence at age
80 to 85 years. However, the standard treatment paradigm for rectal cancer oftentimes …

[HTML][HTML] Management of locally advanced rectal cancer in the elderly: a critical review and algorithm

L Hathout, N Maloney-Patel, U Malhotra… - Journal of …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer incidence and death rates have been declining over the past 10 years.
However, it remains the second leading cause of death in men ages 60–79 and the third …

The role of radiation therapy in the older patient

A Dohm, R Diaz, RH Nanda - Current Oncology Reports, 2021 - Springer
Abstract Purpose of Review Older patients represent a unique subgroup of the cancer
patient population for which the role of radiation therapy (RT) requires special consideration …

Oncologic outcome and morbidity in the elderly rectal cancer patients after preoperative chemoradiotherapy and total mesorectal excision: a multi-institutional and …

SY Sung, HS Jang, SH Kim, JU Jeong, S Jeong… - Annals of …, 2019 - journals.lww.com
Objective: To determine the toxicity and oncologic outcome of neoadjuvant
chemoradiotherapy (CRT) followed by curative total mesorectal excision (TME) in the elderly …

Factors predicting intolerance to definitive conventional radiotherapy in geriatric patients

CH Rim, WS Yoon, JA Lee, DS Yang… - Strahlentherapie …, 2018 - search.proquest.com
Purpose Although radiotherapy can be administered with a relatively low therapeutic
burden, many elderly patients do not complete radiotherapy. In order to predict intolerance …

Preoperative chemoradiotherapy in older patients with rectal cancer guided by comprehensive geriatric assessment within a multidisciplinary team—a multicenter …

WY Liu, Y Tang, N Li, Y Tang, YJ Cheng, L Yang… - BMC geriatrics, 2024 - Springer
Background The purpose of this study was to evaluate the safety and efficacy of
preoperative concurrent chemoradiotherapy (preCRT) for locally advanced rectal cancer in …

Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric …

WY Liu, J Jin, Y Tang, N Li, Y Tang, J Wang… - Journal of Geriatric …, 2021 - Elsevier
Background and purpose Comprehensive geriatric assessment (CGA) is a diagnostic
method to assess the physical and mental health status of older patients. The purpose of this …

Role of Radical Surgery Following Preoperative Chemoradiotherapy in Octogenarians With Rectal Cancer: A SEER Analysis

YJ Lim, M Kong - Anticancer Research, 2024 - ar.iiarjournals.org
Background/Aim: There has been a growing trend toward a watch-and-wait strategy to avoid
surgery. This study evaluated the prognostic outcomes of nonoperative management …