The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …

During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

The placenta is the extraembryonic organ that supports the fetus during intrauterine life.
Although placental dysfunction results in major disorders of pregnancy with immediate and …

Defective placentation is the underlying cause of various pregnancy complications, such as
severe intrauterine growth restriction and preeclampsia. However, studies on human …

Zika virus (ZIKV) infection during pregnancy threatens pregnancy and fetal health. However,
the infectivity and pathological effects of ZIKV on placental trophoblast progenitor cells in …

The human placenta is essential for successful reproduction. There is great variation in the
anatomy and development of the placenta in different species, meaning that animal models …

The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

Correct development of the human placenta and its differentiated epithelial cells, syncytial
trophoblasts (STBs) and extravillous trophoblasts (EVTs), is crucial for a successful …

Implantation involves an extensive cross talk between the trophoblast cells and the receptive
endometrium through embryonic as well as endometrial‐derived factors that regulate the …