Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Paradox of complex diversity: Challenges in the diagnosis and management of bacterial keratitis

RB Singh, S Das, J Chodosh, N Sharma… - Progress in Retinal and …, 2022 - Elsevier
Bacterial keratitis continues to be one of the leading causes of corneal blindness in the
developed as well as the developing world, despite swift progress since the dawn of the …

Epidemiology, microbiology, and genetics of contact lens–related and non–contact lens-related infectious keratitis

F Stapleton, GS Shrestha, AK Vijay, N Carnt - Eye & Contact Lens, 2022 - journals.lww.com
Infectious keratitis is a rare but severe condition associated with a range of ocular and
systemic predisposing conditions, including ocular trauma, prior surgery, surface disease …

Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities

A Petenkova, SA Auger, J Lamb, D Quellier… - Nature …, 2023 - nature.com
The bactericidal function of neutrophils is dependent on a myriad of intrinsic and extrinsic
stimuli. Using systems immunology approaches we identify microbiome-and infection …

Clinical features, risk factors and outcomes of contact lens-related bacterial keratitis in Nottingham, UK: a 7-year study

L Suresh, Y Hammoudeh, CS Ho, ZZ Ong, J Cairns… - Eye, 2024 - nature.com
Abstract Background/Objectives To examine the clinical characteristics, risk factors and
outcomes of contact lens-related bacterial keratitis (CLBK) in a large UK tertiary referral …

A rise in the frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021

RMQ Shanks, S Atta, NA Stella… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Pseudomonas aeruginosa causes vision threatening keratitis. The LasR
transcription factor regulates virulence factors in response to the quorum sensing molecule …

[HTML][HTML] The antibacterial efficacy of high-fluence PACK cross-linking can be accelerated

NJ Lu, H Koliwer-Brandl, F Gilardoni… - … vision science & …, 2023 - iovs.arvojournals.org
Purpose: To determine whether high-fluence photoactivated chromophore for keratitis cross-
linking (PACK-CXL) can be accelerated. Methods: Solutions of Staphylococcus aureus and …

Bacterial microbiota of the contact lens surface and associated care behaviours

L Udomwech, K Karnjana, J Jewboonchu… - Heliyon, 2022 - cell.com
Introduction Contact lens (CL) wear has been reported to cause changes to the microbiome
of the ocular surface. More insight into the alteration of this microenvironment can help to …

Clinical comparative analysis of bacterial keratitis according to contact lens use: a retrospective study in a tertiary referral center of South Korea

CW Moon, CH Cho, SB Lee - International Ophthalmology, 2023 - Springer
Purpose To compare the clinical aspects and treatment outcomes of contact lens-related
bacterial keratitis (CLBK) and non-CLBK patients. Methods Altogether 217 patients of …

Restoration of corneal epithelial barrier function: a possible target for corneal neovascularization

S Shen, Y Zhang - The Ocular Surface, 2024 - Elsevier
Corneal neovascularization (CoNV) is the second leading common cause of vision
impairment worldwide and is a blinding pathological alteration brought on by ocular trauma …