Organophotocatalysed synthesis of 2-piperidinones in one step via [1+ 2+ 3] strategy

YD Du, S Wang, HW Du, XY Chang, XY Chen… - Nature …, 2023 - nature.com
Six-membered N-containing heterocycles, such as 2-piperidinone derivatives, with diverse
substitution patterns are widespread in natural products, drug molecules and serve as key …

Progress of Metal‐Free Visible‐Light‐Driven α‐C− H Functionalization of Tertiary Amines: A Decade Journey

ML Deb, BS Saikia, PJ Borpatra… - Asian Journal of …, 2022 - Wiley Online Library
This review article gives an update on the metal‐free photocatalyzed and photocatalyzed‐
free α‐C− H functionalizations of tertiary amines promoted by visible light. C− H activation is …

Water‐Promoted Carbon‐Carbon Bond Cleavage Employing a Reusable Fe Single‐Atom Catalyst

H Qi, S Mao, J Rabeah, R Qu, N Yang… - Angewandte Chemie …, 2023 - Wiley Online Library
The development of methods for selective cleavage reactions of thermodynamically stable
C− C/C= C bonds in a green manner is a challenging research field which is largely …

Visible-light-mediated efficient metal-free catalyst for α-oxygenation of tertiary amines to amides

Y Zhang, D Riemer, W Schilling, J Kollmann… - ACS Catalysis, 2018 - ACS Publications
A metal-free system has been discovered for the efficient α-oxygenation of tertiary amines to
the corresponding amides using oxygen as an oxidant. This visible-light-mediated …

Oxyfunctionalization of the remote C− H bonds of aliphatic amines by decatungstate photocatalysis

DM Schultz, F Lévesque, DA DiRocco… - Angewandte Chemie …, 2017 - Wiley Online Library
Aliphatic amines, oxygenated at remote positions within the molecule, represent an
important class of synthetic building blocks to which there are currently no direct means of …

Methyl‐Selective α‐Oxygenation of Tertiary Amines to Formamides by Employing Copper/Moderately Hindered Nitroxyl Radical (DMN‐AZADO or 1‐Me‐AZADO)

S Nakai, T Yatabe, K Suzuki, Y Sasano… - Angewandte Chemie …, 2019 - Wiley Online Library
Methyl‐selective α‐oxygenation of tertiary amines is a highly attractive approach for
synthesizing formamides while preserving the amine substrate skeletons. Therefore, the …

Electrosynthesis of N, N-dimethylformamide from market-surplus trimethylamine coupled with hydrogen production

M Jin, AZ Li, Y Wang, J Li, H Zhou, BJ Li, H Duan - Green Chemistry, 2023 - pubs.rsc.org
N, N-Dimethylformamide (DMF) is a universal solvent with wide applications across various
industries. Current industrial synthesis requires high temperature and high pressure, starting …

Metal-free photocatalysts for the oxidation of non-activated alcohols and the oxygenation of tertiary amines performed in air or oxygen

Y Zhang, W Schilling, D Riemer, S Das - Nature Protocols, 2020 - nature.com
This protocol describes the use of 9-fluorenone as a cheap and non-toxic photocatalyst for
the oxidation of non-activated alcohols performed under the irradiation of a blue light …

Development of a hypoxia-triggered and hypoxic radiosensitized liposome as a doxorubicin carrier to promote synergetic chemo-/radio-therapy for glioma

H Liu, Y Xie, Y Zhang, Y Cai, B Li, H Mao, Y Liu, J Lu… - Biomaterials, 2017 - Elsevier
The treatment of malignant primary brain tumors is challenging. Concomitant
radiochemotherapy has become the standard clinical treatment for malignant glioma, but …

Copper catalyzed late-stage C(sp3)-H functionalization of nitrogen heterocycles

Z Chang, J Huang, S Wang, G Chen, H Zhao… - Nature …, 2021 - nature.com
Nitrogen heterocycle represents a ubiquitous skeleton in natural products and drugs. Late-
stage C (sp3)-H bond functionalization of N-heterocycles with broad substrate scope …