NeuroSAFE in radical prostatectomy increases the rate of nerve‐sparing surgery without affecting oncological outcome

MA van Der Slot, MA den Bakker, TSC Tan… - BJU …, 2022 - Wiley Online Library
Objectives To investigate the impact of intra‐operative neurovascular structure‐adjacent
frozen‐section examination (NeuroSAFE) on the rate of nerve‐sparing surgery (NSS) and …

[HTML][HTML] Current applications of ex-vivo fluorescent confocal microscope in urological practice: A systematic review of literature

A Eissa, S Puliatti, NR Peñaranda… - Chinese Clinical …, 2024 - cco.amegroups.org
Background: Histopathological examination, a cornerstone in diagnosing cancer, faces
challenges due to its time-consuming nature. This review explores the potential of ex-vivo …

Digital frozen sections with fluorescence confocal microscopy during robot-assisted radical prostatectomy: surgical technique

B Rocco, L Sarchi, S Assumma, A Cimadamore… - European Urology, 2021 - Elsevier
Background Robot-assisted radical prostatectomy (RARP) involves a tradeoff between
oncological control and functional outcomes. Intraoperative control of surgical margins …

Development and external validation of a novel nomogram to predict side-specific extraprostatic extension in patients with prostate cancer undergoing radical …

TFW Soeterik, HHE van Melick, LM Dijksman… - European Urology …, 2022 - Elsevier
Background Prediction of side-specific extraprostatic extension (EPE) is crucial in selecting
patients for nerve-sparing radical prostatectomy (RP). Objective To develop and externally …

NeuroSAFE frozen section during robot‐assisted radical prostatectomy: peri‐operative and histopathological outcomes from the NeuroSAFE PROOF feasibility …

E Dinneen, A Haider, J Grierson, A Freeman… - BJU …, 2021 - Wiley Online Library
Objectives To report on the methods, peri‐operative outcomes and histopathological
concordance between frozen and final section from the NeuroSAFE PROOF feasibility study …

[HTML][HTML] Urinary incontinence and sexual function after the introduction of NeuroSAFE in radical prostatectomy for prostate cancer

MA van der Slot, S Remmers, GJLH van Leenders… - European urology …, 2023 - Elsevier
Background Nerve-sparing (NS) radical prostatectomy (RP) results in better functional
outcomes. Intraoperative neurovascular structure–adjacent frozen section examination …

Association between oncotype DX genomic prostate score and adverse tumor pathology after radical prostatectomy

MC Moschovas, C Chew, S Bhat, M Sandri… - European urology …, 2022 - Elsevier
Abstract Background The Oncotype DX assay is a clinically validated 17-gene genomic
assay that provides a genomic prostate score (GPS; scale 0–100) measuring the …

Intraoperative technologies to assess margin status during radical prostatectomy–a narrative review

O Windisch, M Diana, D Tilki, G Marra… - Prostate Cancer and …, 2024 - nature.com
Positive surgical margin (PSM) is a frequent concern for surgeons performing radical
prostatectomy for prostate cancer (PCa). PSM are recognized as risk factors for earlier …

Diagnostic ability of Ga-68 PSMA PET to detect dominant and non-dominant tumors, upgrading and adverse pathology in patients with PIRADS 4–5 index lesions …

E Koseoglu, Y Kordan, M Kilic, O Sal… - Prostate Cancer and …, 2021 - nature.com
Background To evaluate the additive role of Ga-68 PSMA PET as a primary staging tool in
patients bearing prostate cancer in single PIRADS 4 or 5 index lesions. Methods Eighty-one …

“Real-time” assessment of surgical margins during radical prostatectomy: state-of-the-art

A Eissa, A Zoeir, MC Sighinolfi, S Puliatti… - Clinical Genitourinary …, 2020 - Elsevier
Histopathologic examination of the pathologic specimens using hematoxylin & eosin stains
represents the backbone of the modern pathology. It is time-consuming; thus,“real-time” …