Carbon monoxide poisoning: pathogenesis, management, and future directions of therapy

JJ Rose, L Wang, Q Xu, CF McTiernan… - American journal of …, 2017 - atsjournals.org
Carbon monoxide (CO) poisoning affects 50,000 people a year in the United States. The
clinical presentation runs a spectrum, ranging from headache and dizziness to coma and …

Nanoscale metal‐organic frameworks: synthesis, biocompatibility, imaging applications, and thermal and dynamic therapy of tumors

S Li, L Tan, X Meng - Advanced Functional Materials, 2020 - Wiley Online Library
Nanoscale metal‐organic frameworks (NMOFs) have attracted increasing attention for
biomedical applications due to their large specific surface area, good biocompatibility …

Carbon Monoxide Poisoning: From Microbes to Therapeutics

MR Dent, JJ Rose, J Tejero… - Annual review of …, 2024 - annualreviews.org
Carbon monoxide (CO) poisoning leads to 50,000–100,000 emergency room visits and
1,500–2,000 deaths each year in the United States alone. Even with treatment, survivors …

Mechanisms and therapeutic targets of carbon monoxide poisoning: a focus on reactive oxygen species

T Wang, Y Zhang - Chemico-biological interactions, 2024 - Elsevier
Carbon monoxide (CO) poisoning presents a substantial public health challenge that
necessitates the identification of its pathological mechanisms and therapeutic targets. CO …

Five-coordinate H64Q neuroglobin as a ligand-trap antidote for carbon monoxide poisoning

I Azarov, L Wang, JJ Rose, Q Xu, XN Huang… - Science translational …, 2016 - science.org
Carbon monoxide (CO) is a leading cause of poisoning deaths worldwide, with no available
antidotal therapy. We introduce a potential treatment paradigm for CO poisoning, based on …

Extracorporeal membrane oxygenators with light‐diffusing fibers for treatment of carbon monoxide poisoning: Experiments, mathematical modeling, and performance …

J Childs, A Fischbach, A Smirnov… - Lasers in Surgery …, 2023 - Wiley Online Library
Abstract Background and Objectives Approximately 50,000 emergency department visits per
year due to carbon monoxide (CO) poisoning occur in the United States alone. Tissue …

Phototherapy and extracorporeal membrane oxygenation facilitate removal of carbon monoxide in rats

L Zazzeron, A Fischbach, W Franco… - Science Translational …, 2019 - science.org
Inhaled carbon monoxide (CO) displaces oxygen from hemoglobin, reducing the capacity of
blood to carry oxygen. Current treatments for CO-poisoned patients involve administration of …

Pharmacokinetic characteristics of carbon monoxide

X Yang, M Wang, C Tan, W Lu… - Carbon Monoxide in …, 2022 - Wiley Online Library
In a historical context, it is important to note that carbon monoxide (CO) was first recognized
as a poisonous gas long before the discovery of its physiological signaling roles. Before the …

James Watt, of steam engine fame, offered inhaled carbon monoxide for putative therapeutic action

OW Xu, J Wang, TA Alston - Anesthesia & Analgesia, 2025 - journals.lww.com
Abstract James Watt (1736–1819) is remembered as a steam engine innovator and
industrial magnate. A polymath, he was also a hands-on contributor to the Medical …

[HTML][HTML] Carbon monoxide poisoning: A problem uniquely suited to a medicinal inorganic chemistry solution

AL Parker, TC Johnstone - Journal of inorganic biochemistry, 2024 - Elsevier
Carbon monoxide poisoning is one of the most common forms of poisoning in the world.
Although the primary mode of treatment, oxygen therapy, is highly effective in many cases …