Paracoccidioidomycosis (PCM), initially reported in 1908 in the city of São Paulo, Brazil, by
Adolpho Lutz, is primarily a systemic and neglected tropical mycosis that may affect …

Macrophages are innate immune cells that possess unique abilities to polarize toward
different phenotypes. Classically activated macrophages are known to have major roles in …

Advances in the glycobiology and immunology fields have provided many insights into the
role of carbohydrate-protein interactions in the immune system. We aim to present a …

An efficient oxidative stress response is important to the fungal pathogen Paracoccidioides
to survive within the human host. In this study, oxidative stress was mimicked by exposure of …

Nonprotective immune responses to highly virulent Cryptococcus neoformans strains, such
as H99, are associated with Th2-type cytokine production, alternatively activated …

This study aimed to investigate the immunological mechanisms involved in the gender
distinct incidence of paracoccidioidomycosis (pcm), an endemic systemic mycosis in Latin …

Paracoccidioidomycosis is an endemic fungal infection of pulmonary origin that
disseminates to different sites, notably oral mucous membranes, adrenal glands …

Non-protective immune responses to highly virulent Cryptococcus neoformans strains, such
as H99, are associated with Th2-type cytokine production, alternatively activated …

Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with
Paracoccidioides brasiliensis and P. lutzii being the causal agents of this disorder. Several …

Protective immunity against Paracoccidioides consists of a stepwise activation of numerous
effector mechanisms that comprise many cellular and soluble components. At the initial …