Liquid chromatography coupled to tandem mass spectrometry (LC‐MS/MS) is now the main
analytical method for the identification and quantification of peptides and proteins in …

Post translational modifications (PTMs) are covalent modifications of proteins that can range
from small chemical modifications to addition of entire proteins. PTMs contribute to …

A recent paper in Science Advances by Sun et al. claims that intra-chloroplast proteins in the
model plant Arabidopsis can be polyubiquitinated and then extracted into the cytosol for …

The use of concentrated ionic liquids (ILs) in the bioanalytical chemistry of proteins is
sparse; typically, dilute aqueous IL solutions are used. Concentrated ILs have unique …

Simple Summary Trypsin is frequently employed to cleave proteins ahead of mass
spectrometry characterization. Traditionally, enzyme digestion involves overnight incubation …

Background DNA damage response plays critical roles in tumor pathogenesis and
radiotherapy resistance. Protein phosphorylation is a critical mechanism in regulation of …

Post-translational oxidation of methionine residues can destabilize proteins or modify their
functions. Although levels of methionine oxidation can provide important information …

Mass spectrometry (MS) is one of the main techniques for protein identification. Herein, MS
has been employed for the identification of bovine serum albumin (BSA), which was …

Purpose Affibodies are a class of versatile affinity proteins with a wide variety of therapeutic
applications, ranging from contrast agents for imaging to cell-targeting therapeutics. We …

With current mass spectrometry and bioinformatics platforms, proteome analysis is at the
forefront of characterizing complex biological systems. Through deep qualitative coverage …