The economic impact of machine perfusion technology in liver transplantation

YL Boteon, AJ Hessheimer, IMA Brüggenwirth… - Artificial …, 2022 - Wiley Online Library
Introduction Several clinical studies have demonstrated the safety, feasibility, and efficacy of
machine perfusion in liver transplantation, although its economic outcomes are still …

Extracorporeal cardiopulmonary resuscitation dissemination and integration with organ preservation in the USA: ethical and logistical considerations

T Schiff, C Koziatek, E Pomerantz, N Bosson… - Critical Care, 2023 - Springer
Use of extracorporeal membrane oxygenation (ECMO) in cardiopulmonary resuscitation,
termed eCPR, offers the prospect of improving survival with good neurological function after …

Cellular recovery after prolonged warm ischaemia of the whole body

D Andrijevic, Z Vrselja, T Lysyy, S Zhang, M Skarica… - Nature, 2022 - nature.com
After cessation of blood flow or similar ischaemic exposures, deleterious molecular
cascades commence in mammalian cells, eventually leading to their death,. Yet with …

Maintaining the permanence principle of death during normothermic regional perfusion in controlled donation after the circulatory determination of death: Results of a …

M Royo-Villanova, E Miñambres, JM Sánchez… - American Journal of …, 2024 - Elsevier
One concern about the use of normothermic regional perfusion (NRP) in controlled donation
after the circulatory determination of death (cDCD) is that the brain may be perfused. We …

[HTML][HTML] Normothermic regional perfusion can improve both utilization and outcomes in DCD liver, kidney, and pancreas transplantation

Y Bekki, KP Croome, B Myers, K Sasaki… - Transplantation …, 2023 - journals.lww.com
Background. Normothermic regional perfusion (NRP) has gained widespread adoption in
multiple European countries. The aim of this study was to examine the influence of …

Consensus statement on normothermic regional perfusion in donation after circulatory death: Report from the European Society for Organ Transplantation's Transplant …

I Jochmans, AJ Hessheimer, AP Neyrinck… - Transplant …, 2021 - Wiley Online Library
Normothermic regional perfusion (NRP) in donation after circulatory death (DCD) is a safe
alternative to in situ cooling and rapid procurement. An increasing number of countries and …

Understanding the brain-based determination of death when organ recovery is performed with DCDD in situ normothermic regional perfusion

JL Bernat, B Domínguez-Gil, AK Glazier… - …, 2023 - journals.lww.com
The brain-based determination of death (“brain death”) is now widely accepted throughout
the world. It states that the irreversible cessation of brain functions is the fundamental …

[HTML][HTML] Normothermic regional perfusion and hypothermic oxygenated machine perfusion for livers donated after controlled circulatory death with prolonged warm …

D Patrono, M Zanierato, M Vergano… - Transplant …, 2022 - frontierspartnerships.org
Prolonged warm ischemia time (WIT) has a negative prognostic value in liver transplantation
(LT) using grafts procured after circulatory death (DCD). To assess the value of abdominal …

Restoring the organism as a whole: Does NRP resurrect the dead?

EJN Busch - The American Journal of Bioethics, 2024 - Taylor & Francis
The introduction of normothermic regional perfusion (NRP) in controlled donation after
circulatory determination of death (cDCDD) protocols is by some regarded as controversial …

Normothermic regional perfusion in controlled DCD liver procurement: Outcomes of the Swedish national implementation protocol

E Bluhme, M Gäbel, LM de la Maza, V Nilsén… - Liver …, 2024 - journals.lww.com
Liver transplantation (LTX) using donors after controlled circulatory death (cDCD) is
associated with poorer graft survival and increased incidence of nonanastomotic biliary …