An insight into the medicinal perspective of synthetic analogs of indole: A review

PV Thanikachalam, RK Maurya, V Garg… - European journal of …, 2019 - Elsevier
Heterocycles occupy a salient place in chemistry due to their wide range of activity in the
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …

Recent progress in biological activities of indole and indole alkaloids

TP Singh, OM Singh - Mini reviews in medicinal chemistry, 2018 - ingentaconnect.com
The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …

A review exploring biological activities of hydrazones

G Verma, A Marella, M Shaquiquzzaman… - Journal of Pharmacy …, 2014 - journals.lww.com
The development of novel compounds, hydrazones has shown that they possess a wide
variety of biological activities viz. antimicrobial, anticonvulsant, antidepressant, anti …

Mannich bases in medicinal chemistry and drug design

G Roman - European journal of medicinal chemistry, 2015 - Elsevier
The biological activity of Mannich bases, a structurally heterogeneous class of chemical
compounds that are generated from various substrates through the introduction of an …

Isatin hybrids and their anti-tuberculosis activity

Z Xu, S Zhang, C Gao, J Fan, F Zhao, ZS Lv… - Chinese Chemical …, 2017 - Elsevier
Tuberculosis (TB) is one of the most common and even fatal infectious diseases known to
mankind. Millions of new cases are reported every year over the world, and one-third of the …

Antibacterial and antioxidant activities for natural and synthetic dual-active compounds

G Martelli, D Giacomini - European Journal of Medicinal Chemistry, 2018 - Elsevier
Antimicrobial resistance is widely recognized as a grave threat to global health in the 21st
century, since the past decades have seen a dramatic increase in human-pathogenic …

[PDF][PDF] Biological importance of the indole nucleus in recent years: a comprehensive review

V Sharma, P Kumar, D Pathak - Journal of Heterocyclic Chemistry, 2010 - academia.edu
Heterocyclic compounds are those cyclic compounds in which one or more of the ring
carbons are replaced by another atom. The non-carbon atoms in such rings are referred to …

4-Quinolone hybrids and their antibacterial activities

YQ Hu, S Zhang, Z Xu, ZS Lv, ML Liu… - European Journal of …, 2017 - Elsevier
The emergence and wide-spread of drug-resistant bacteria including multi-drug resistant
and pan-drug resistant pathogens which are associated with considerable mortality …

Medicinal significance of benzothiazole scaffold: an insight view

PC Sharma, A Sinhmar, A Sharma… - Journal of enzyme …, 2013 - Taylor & Francis
Heterocycles bearing nitrogen, sulphur and thiazole moieties constitute the core structure of
a number of biologically interesting compounds. Benzothiazole, a group of xenobiotic …

Design and synthesis of heterocyclic azole based bioactive compounds: Molecular structures, quantum simulation, and mechanistic studies through docking as multi …

J Haribabu, V Garisetti, RE Malekshah… - Journal of molecular …, 2022 - Elsevier
Abstract Two heterocyclic azole compounds, 3-(2, 3-dihydrobenzo [d] thiazol-2-yl)-4H-
chromen-4-one (SVS1) and 5-(1H-indol-3-yl)-4-methyl-2, 4-dihydro-3H-1, 2, 4-triazole-3 …