Increasing evidence indicates lithium (Li+) efficacy in neuropsychiatry, pointing to
overlapping mechanisms that occur within distinct neuronal populations. In fact, the same …

Here an overview is provided on therapeutic/neuroprotective effects of Lithium (Li+) in
neurodegenerative and psychiatric disorders focusing on the conspicuous action of Li+ …

Lithium therapy received approval during the 1970s, and it has been used for its
antidepressant, antimanic, and anti-suicidal effects for acute and long-term prophylaxis and …

Inositol depletion is a hypothesized mechanism of action of mood stabilization drugs used in
the treatment of bipolar disorder. It was previously reported that the mood stabilizer …

Metal ions are critical to a wide range of biological processes. Among them, lithium (Li) has
been recognised for its benefit as a treatment for bipolar disorder (BD). However, we are yet …

Inositol monophosphatase (IMPase) is an enzyme with two homologs—IMPA1 and IMPA2—
that is responsible for dephosphorylating myo-inositol monophosphate to generate myo …

Anaerobic digestion stands as a key technology in the emerging green energy economy. Mg
2+ has been identified as an important element to improve digesters methane production; …

Lithium is drug for bipolar disorders with a narrow therapeutic window. Lithium was recently
reported to prevent stroke and protect vascular endothelium but tends to accumulate …

Therapeutic implications of Li+, in many cases, stem from its ability to inhibit certain Mg 2+-
dependent enzymes, where it interacts with or substitutes for Mg 2+. The underlying details …

Staphylococcus aureus is a commensal and opportunistic pathogen that causes lethal
infections. Biofilm forming ability of S. aureus enhances its virulence since biofilm provides …