Advancing Predictive Risk Assessment of Chemicals via Integrating Machine Learning, Computational Modeling, and Chemical/Nano‐Quantitative Structure‐Activity …

AV Singh, M Varma, M Rai… - Advanced Intelligent …, 2024 - Wiley Online Library
The escalating use of novel chemicals and nanomaterials (NMs) across diverse sectors
underscores the need for advanced risk assessment methods to safeguard human health …

[HTML][HTML] Nano-QSAR modeling for predicting the cytotoxicity of metallic and metal oxide nanoparticles: A review

J Li, C Wang, L Yue, F Chen, X Cao, Z Wang - … and Environmental Safety, 2022 - Elsevier
Given the rapid development of nanotechnology, it is crucial to understand the effects of
nanoparticles on living organisms. However, it is laborious to perform toxicological tests on a …

Understanding nanoparticle toxicity to direct a safe-by-design approach in cancer nanomedicine

JA Damasco, S Ravi, JD Perez, DE Hagaman… - Nanomaterials, 2020 - mdpi.com
Nanomedicine is a rapidly growing field that uses nanomaterials for the diagnosis, treatment
and prevention of various diseases, including cancer. Various biocompatible nanoplatforms …

Practices and trends of machine learning application in nanotoxicology

I Furxhi, F Murphy, M Mullins, A Arvanitis, CA Poland - Nanomaterials, 2020 - mdpi.com
Machine Learning (ML) techniques have been applied in the field of nanotoxicology with
very encouraging results. Adverse effects of nanoforms are affected by multiple features …

Core, coating, or corona? The importance of considering protein coronas in nano-QSPR modeling of zeta potential

S Sengottiyan, A Mikolajczyk, K Jagiełło, M Swirog… - Acs Nano, 2023 - ACS Publications
To control stability in a biological medium, several factors affecting the zeta potential (ζ) of
nanoparticles (NPs) must be considered, including complex interactions between the …

Molecular mechanisms, characterization methods, and utilities of nanoparticle biotransformation in nanosafety assessments

X Cai, X Liu, J Jiang, M Gao, W Wang, H Zheng, S Xu… - Small, 2020 - Wiley Online Library
It is a big challenge to reveal the intrinsic cause of a nanotoxic effect due to diverse
branches of signaling pathways induced by engineered nanomaterials (ENMs) …

Nanotoxicology data for in silico tools: a literature review

I Furxhi, F Murphy, M Mullins, A Arvanitis… - Nanotoxicology, 2020 - Taylor & Francis
The exercise of non-testing approaches in nanoparticles (NPs) hazard assessment is
necessary for the risk assessment, considering cost and time efficiency, to identify, assess …

Toward rigorous materials production: New approach methodologies have extensive potential to improve current safety assessment practices

P Nymark, M Bakker, S Dekkers, R Franken… - Small, 2020 - Wiley Online Library
Advanced material development, including at the nanoscale, comprises costly and complex
challenges coupled to ensuring human and environmental safety. Governmental agencies …

Machine learning prediction of nanoparticle in vitro toxicity: A comparative study of classifiers and ensemble-classifiers using the Copeland Index

I Furxhi, F Murphy, M Mullins, CA Poland - Toxicology letters, 2019 - Elsevier
Abstract Nano-Particles (NPs) are well established as important components across a broad
range of products from cosmetics to electronics. Their utilization is increasing with their …

A comprehensive systematic literature review of ML in nanotechnology for sustainable development

I Ur Rehman, I Ullah, H Khan, MS Guellil… - Nanotechnology …, 2024 - degruyter.com
The rapid expansion of nanotechnology has transformed numerous sectors, with
nanoproducts now ubiquitous in everyday life, electronics, healthcare, and pharmaceuticals …