Imaging and photodynamic therapy: mechanisms, monitoring, and optimization

JP Celli, BQ Spring, I Rizvi, CL Evans… - Chemical …, 2010 - ACS Publications
The purpose of this review is to present the current state of the role of imaging in
photodynamic therapy (PDT). For the reader to fully appreciate the context of the discussions …

Conjugated photosensitizers for imaging and PDT in cancer research

JCS Simões, S Sarpaki… - Journal of medicinal …, 2020 - ACS Publications
Early cancer detection and perfect understanding of the disease are imperative toward
efficient treatments. It is straightforward that, for choosing a specific cancer treatment …

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

M Mitsunaga, M Ogawa, N Kosaka, LT Rosenblum… - Nature medicine, 2011 - nature.com
Three major modes of cancer therapy (surgery, radiation and chemotherapy) are the
mainstay of modern oncologic therapy. To minimize the side effects of these therapies …

[HTML][HTML] Unique diagnostic and therapeutic roles of porphyrins and phthalocyanines in photodynamic therapy, imaging and theranostics

LB Josefsen, RW Boyle - Theranostics, 2012 - ncbi.nlm.nih.gov
Porphyrinic molecules have a unique theranostic role in disease therapy; they have been
used to image, detect and treat different forms of diseased tissue including age-related …

Development and applications of photo-triggered theranostic agents

P Rai, S Mallidi, X Zheng, R Rahmanzadeh… - Advanced drug delivery …, 2010 - Elsevier
Theranostics, the fusion of therapy and diagnostics for optimizing efficacy and safety of
therapeutic regimes, is a growing field that is paving the way towards the goal of …

A three‐dimensional in vitro ovarian cancer coculture model using a high‐throughput cell patterning platform

F Xu, J Celli, I Rizvi, S Moon, T Hasan… - Biotechnology …, 2011 - Wiley Online Library
In vitro 3D cancer models that provide a more accurate representation of disease in vivo are
urgently needed to improve our understanding of cancer pathology and to develop better …

[HTML][HTML] The impact of microfluidics in high-throughput drug-screening applications

P De Stefano, E Bianchi, G Dubini - Biomicrofluidics, 2022 - pubs.aip.org
Drug discovery is an expensive and lengthy process. Among the different phases, drug
discovery and preclinical trials play an important role as only 5–10 of all drugs that begin …

Photonanomedicine: a convergence of photodynamic therapy and nanotechnology

G Obaid, M Broekgaarden, AL Bulin, HC Huang… - Nanoscale, 2016 - pubs.rsc.org
As clinical nanomedicine has emerged over the past two decades, phototherapeutic
advancements using nanotechnology have also evolved and impacted disease …

Optical fibers for high-resolution in vivo microendoscopic fluorescence imaging

G Oh, E Chung, SH Yun - Optical Fiber Technology, 2013 - Elsevier
Optical fiber-based high-resolution fluorescence imaging techniques have promising
applications in clinical practice and preclinical research using animals. Here we review the …

Photodynamic therapy, priming and optical imaging: Potential co-conspirators in treatment design and optimization—a Thomas Dougherty Award for Excellence in …

P De Silva, MA Saad, HC Thomsen, S Bano… - Journal of Porphyrins …, 2020 - World Scientific
Photodynamic therapy is a photochemistry-based approach, approved for the treatment of
several malignant and non-malignant pathologies. It relies on the use of a non-toxic, light …