The histiocytoses are rare disorders characterized by the accumulation of macrophage,
dendritic cell, or monocyte-derived cells in various tissues and organs of children and adults …

Macrophage activation syndrome (MAS) refers to acute overwhelming inflammation caused
by a'cytokine storm'. Although increasingly recognized as a life-threatening complication of …

In HLH‐94, the first prospective international treatment study for hemophagocytic
lymphohistiocytosis (HLH), diagnosis was based on five criteria (fever, splenomegaly …

Macrophage activation syndrome (MAS) is a severe, frequently fatal complication of
systemic juvenile idiopathic arthritis (sJIA) with features of hemophagocytosis leading to …

Objectives. Various autoantibodies are detected in the sera of PM/DM patients. Some of
them are specific to PM/DM patients and closely associated with clinical manifestations of …

Macrophage activation syndrome (MAS) is a serious complication of childhood systemic
inflammatory disorders that is thought to be caused by excessive activation and proliferation …

Background Adalimumab is indicated for the treatment of moderate to severe psoriasis in
adults. We assessed the efficacy and safety of adalimumab in children and adolescents with …

Macrophage activation syndrome: advances towards understandi... : Current Opinion in
Rheumatology Macrophage activation syndrome: advances towards understanding …

Focuses on the management of children with hemophagocytic lymphohistiocytosis (HLH),
an autosomal recessive disease. Conditions leading to HLH; Cardinal symptoms of familial …

Objective To design and validate a new questionnaire for identifying patients with
methotrexate (MTX) intolerance, and to determine the prevalence of MTX intolerance in …