Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that recently re-emerged in
many parts of the world causing large-scale outbreaks. CHIKV infection presents as a febrile …

Chikungunya virus (CHIKV), a reemerging arbovirus, causes a crippling musculoskeletal
inflammatory disease in humans characterized by fever, polyarthralgia, myalgia, rash, and …

Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …

Chikungunya (CHIK) is a disabling and debilitating zoonotic disease of humans caused by
the Chikungunya virus (CHIKV), which is transmitted by CHIKV-infected Aedes spp …

Sensitization of the humoral immune response to invading viruses and production of
antiviral antibodies forms part of the host antiviral repertoire. Paradoxically, for a number of …

Background Chikungunya virus—a mosquito-borne alphavirus—is endemic in Africa and
south and southeast Asia and has recently emerged in the Caribbean. No drugs or vaccines …

Beginning in 2004, chikungunya virus (CHIKV) went from an endemic pathogen limited to
Africa and Asia that caused periodic outbreaks to a global pathogen. Given that outbreaks …

Background: Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that circulates
predominantly in tropical and subtropical regions, potentially affecting over 1 billion people …

Background Chikungunya disease, which results in incapacitating arthralgia, has been
reported worldwide. We developed a live-attenuated chikungunya virus (CHIKV) vaccine …

Recombinant nucleic acids are considered as promising next-generation vaccines. These
vaccines express the native antigen upon delivery into tissue, thus mimicking live attenuated …