Microneme proteins in apicomplexans

VB Carruthers, FM Tomley - Molecular mechanisms of parasite invasion …, 2008 - Springer
The invasive stages (zoites) of most apicomplexan parasites are polarised cells that use
their actinomyosin-powered gliding motility or “glideosome” system to move over surfaces …

Plasmodium knowlesi malaria: current research perspectives

A Amir, FW Cheong, J Ryan de Silva… - Infection and drug …, 2018 - Taylor & Francis
Originally known to cause simian malaria, Plasmodium knowlesi is now known as the fifth
human malaria species. Since the publishing of a report that largely focused on human …

[HTML][HTML] Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies

RO Payne, SE Silk, SC Elias, KH Milne, TA Rawlinson… - JCI insight, 2017 - ncbi.nlm.nih.gov
BACKGROUND. Plasmodium vivax is the most widespread human malaria geographically;
however, no effective vaccine exists. Red blood cell invasion by the P. vivax merozoite …

[HTML][HTML] Plasmodium vivax invasion of human erythrocytes inhibited by antibodies directed against the Duffy binding protein

BT Grimberg, R Udomsangpetch, J Xainli… - PLoS …, 2007 - journals.plos.org
Background Plasmodium vivax invasion requires interaction between the human Duffy
antigen on the surface of erythrocytes and the P. vivax Duffy binding protein (PvDBP) …

Sulphated tyrosines mediate association of chemokines and Plasmodium vivax Duffy binding protein with the Duffy antigen/receptor for chemokines (DARC)

H Choe, MJ Moore, CM Owens, PL Wright… - Molecular …, 2005 - Wiley Online Library
Plasmodium vivax is one of four Plasmodium species that cause human malaria. P. vivax
and a related simian malaria parasite, Plasmodium knowlesi, invade erythrocytes by binding …

[HTML][HTML] Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody

TA Rawlinson, NM Barber, F Mohring, JS Cho… - Nature …, 2019 - nature.com
The most widespread form of malaria is caused by Plasmodium vivax. To replicate, this
parasite must invade immature red blood cells through a process requiring interaction of the …

Bacterially expressed and refolded receptor binding domain of Plasmodium falciparum EBA-175 elicits invasion inhibitory antibodies

KC Pandey, S Singh, P Pattnaik, CR Pillai… - Molecular and …, 2002 - Elsevier
Malaria parasites make specific receptor–ligand interactions to invade erythrocytes. A 175
kDa Plasmodium falciparum erythrocyte binding antigen (EBA-175) binds sialic acid …

Targeting the Plasmodium vivax Duffy-binding protein

CE Chitnis, A Sharma - Trends in parasitology, 2008 - cell.com
Plasmodium vivax requires interaction with the Duffy antigen receptor for chemokines
(DARC) to enable its invasion of human erythrocytes. Interaction with DARC is mediated by …

Targeted deletion of Plasmodium knowlesi Duffy binding protein confirms its role in junction formation during invasion

AP Singh, H Ozwara, CHM Kocken… - Molecular …, 2005 - Wiley Online Library
Red cell invasion by Plasmodium merozoites involves multiple steps such as attachment,
apical reorientation, junction formation and entry into a parasitophorous vacuole. These …

Potential role of vaccines in elimination of Plasmodium vivax

M White, CE Chitnis - Parasitology International, 2022 - Elsevier
The unique biology of Plasmodium vivax, with its ability to form latent hypnozoites in the liver
stage and the early appearance of gametocytes during blood stage infection, makes it …