Cytoplasmic vacuolization (also called cytoplasmic vacuolation) is a well-known
morphological phenomenon observed in mammalian cells after exposure to bacterial or viral …

Endophytic fungi are microorganisms that exist almost ubiquitously inside the various
tissues of living plants where they act as an important reservoir of diverse bioactive …

Covering: 2000 to 2023 This review presents the exceptional story of ophiobolin A (OphA)
and sphaeropsidin A (SphA), a sesterterpene and a diterpene, respectively, which were …

Ophiobolins (Ophs) are a group of tricarbocyclic sesterterpenoids whose structures contain
a tricyclic 5-8-5 carbotricyclic skeleton. Thus far, 49 natural Ophs have been reported and …

Ophiobolin A is a fungal secondary metabolite that was found to have significant activity
against apoptosis-resistant glioblastoma cells through the induction of a non-apoptotic cell …

Globally, breast cancer is a primary contributor to cancer-related fatalities and illnesses
among women. Consequently, there is a pressing need for safe and effective treatments for …

Fourteen previously undescribed sesterterpenoids (1–14) were isolated from Bipolaris
maydis. Their structures with absolute configurations were elucidated by NMR, HRESIMS …

Covering: January 2012 to January 2018 Sesterterpenoids are a small family of terpenes
that often possess intriguing biological profiles and complicated chemical structures. Their …

Introduction Since ancient times medicinal plants have been used as medicine in many
parts of the world to promote human health and longevity. In recent years many novel …

Abstract Bipolarins A–H (1–8), eight new tetracyclic ophiobolin-type sesterterpenes featuring
a rare oxaspiro [4.4] nonane moiety, were isolated from cultures of fungus Bipolaris sp …