Bioactive compounds in berries may scavenge reactive oxygen and nitrogen species by
donating electrons to free radicals, thereby protecting DNA, proteins, and lipids from …

Structural information on protein–protein interactions (PPIs) is essential for improved
understanding of regulatory interactome networks that confer various physiological and …

Mitochondria adapt to increased energy demands during muscle contraction by acutely
altering metabolite fluxes and substrate oxidation. With age, an impaired mitochondrial …

The subcellular compartment-specific molecular interactions (SCSIs) are the building blocks
for most molecular functions, biological processes and disease pathogeneses. Extensive …

Recently, several mass spectrometry methods have utilized protein structural stability for the
quantitative study of protein–ligand engagement. These protein-denaturation approaches …

In modern biomedical research, cultivable cell lines are an indispensable tool, and the
selection of cell lines that exhibit specific functional profiles is often critical to success …

Mitochondria are densely packed with proteins, of which most are involved physically or
more transiently in protein–protein interactions (PPIs). Mitochondria host among others all …

Almost every organ consists of many cell types, each with its unique functions. Proteomes of
these cell types are thus unique too. But it is reasonable to assume that interactome (inter …

Sarcopenia, the age-related loss of muscle mass and function, contributes to decreased
quality of life in the elderly and increased healthcare costs. Decreased skeletal muscle …

Proteins carry out the vast majority of biological function inside living cells. They do so by
changing their shapes, interacting with one another and other molecules such as DNA and …