The anti-tumor effect of aspirin: what we know and what we expect

J Ma, Z Cai, H Wei, X Liu, Q Zhao, T Zhang - Biomedicine & …, 2017 - Elsevier
Aspirin has been widely used as an antipyretic analgesic drug. More and more evidences
have shown that aspirin may be play some role on anti-tumor. In this article, we reviewed the …

Aspirin use and endometrial cancer risk and survival

T Takiuchi, EA Blake, K Matsuo, AK Sood… - Gynecologic …, 2018 - Elsevier
The role of acetylsalicylic acid (aspirin) as a chemo-preventive and adjuvant therapeutic
agent for cancers is generating attention. Mounting evidence indicates that aspirin reduces …

Evaluation of aspirin use with cancer incidence and survival among older adults in the prostate, lung, colorectal, and ovarian cancer screening trial

HA Loomans-Kropp, P Pinsky, A Umar - JAMA network open, 2021 - jamanetwork.com
Importance Many studies have evaluated the long-term benefits of aspirin use; however, the
association of aspirin use with cancer incidence and survival in older individuals remains …

Aspirin induces Beclin-1-dependent autophagy of human hepatocellular carcinoma cell

Z Huang, W Fang, W Liu, L Wang, B Liu, S Liu… - European journal of …, 2018 - Elsevier
Aspirin not only reduces the incidence of hepatocellular carcinoma (HCC) but also plays a
synergistic role with chemotherapy for HCC treatment. However, the underlying mechanisms …

Aspirin, NSAID, and acetaminophen use and the risk of endometrial cancer

AN Viswanathan, D Feskanich, ES Schernhammer… - Cancer research, 2008 - AACR
To date, no prospective studies have explored the relationship between the use of aspirin,
other nonsteroidal anti-inflammatory medications (NSAID), and acetaminophen and …

Role of canonical Wnt signaling in endometrial carcinogenesis

TH Dellinger, K Planutis, KS Tewari… - Expert review of …, 2012 - Taylor & Francis
While the role of Wnt signaling is well established in colorectal carcinogenesis, its function in
gynecologic cancers has not been elucidated. Here, we describe the current state of …

Silver nanoparticle-activated COX2/PGE2 axis involves alteration of lung cellular senescence in vitro and in vivo

B Chen, Q Chai, S Xu, Q Li, T Wu, S Chen… - … and Environmental Safety, 2020 - Elsevier
Silver nanoparticles (AgNPs) are widely used as antimicrobial agents and resulted in their
accumulation in environment. The purpose of this study was to investigate the detailed …

Carboranyl derivatives of rofecoxib with cytostatic activity against human melanoma and colon cancer cells

A Buzharevski, S Paskaš, MB Sárosi, M Laube… - Scientific Reports, 2020 - nature.com
Owing to the involvement of cyclooxygenase-2 (COX-2) in carcinogenesis, COX-2-selective
inhibitors are increasingly studied for their potential cytotoxic properties. Moreover, the …

Variances in the level of COX-2 and iNOS in different grades of endometrial cancer

M Oplawski, K Dziobek, N Zmarzły… - Current …, 2020 - ingentaconnect.com
Background: Many experimental studies have demonstrated the importance of COX-2 in the
tumor angiogenesis. Inducible iNOS is responsible for a high and stable level of nitric oxide …

Effects of a selective COX-2 inhibitor in patients with uterine endometrial cancers

K Hasegawa, Y Torii, R Ishii, S Oe, R Kato… - Archives of gynecology …, 2011 - Springer
Purpose COX-2 is highly expressed in endometrial cancers, suggesting that a selective COX-
2 inhibitor could be valuable for treating endometrial cancers that overexpress COX-2. In this …