Coupling 3D printing with hot-melt extrusion to produce controlled-release tablets

J Zhang, X Feng, H Patil, RV Tiwari… - International journal of …, 2017 - Elsevier
The main objective of this work was to explore the potential of coupling fused deposition
modeling in three-dimensional (3D) printing with hot-melt extrusion (HME) technology to …

[PDF][PDF] A summary of recent advances in ocular inserts and implants

LP Jervis - J. Bioequiv. Bioavailab, 2017 - academia.edu
With the physiological and anatomical constraints put forth by the eye it is a significant
challenge to the pharmaceutical scientists to target drugs to the posterior segment of the …

Lipid nanoparticles of zaleplon for improved oral delivery by Box–Behnken design: optimization, in vitro and in vivo evaluation

N Dudhipala, KY Janga - Drug development and industrial …, 2017 - Taylor & Francis
Purpose: Zaleplon (ZL) is a hypnotic drug prescribed for the management of insomnia and
convulsions. The oral bioavailability of ZL was low (∼ 30%) owing to poor water solubility …

[HTML][HTML] A systemic review on lifestyle interventions to reduce blood pressure

S Vooradi, UV Mateti - Journal of Health Research and Reviews …, 2016 - journals.lww.com
Hypertension (HTN) is considered a major predominant disease with different comorbidities
such as diabetes and cardiovascular and renal disorders. Pharmacological methods in …

Competence of raloxifene hydrochloride loaded liquisolid compacts for improved dissolution and intestinal permeation

DR Komala, KY Janga, R Jukanti, S Bandari… - Journal of Drug Delivery …, 2015 - Elsevier
The primary purpose of this research is to formulate raloxifene hydrochloride (RXH) loaded
liquisolid compacts for improved dissolution behavior and intestinal permeation. Owing to …

Micronized Zaleplon Delivery via Orodispersible Film and Orodispersible Tablets

P Manda, C Popescu, A Juluri, K Janga… - AAPS …, 2018 - Springer
The following research study focuses on improving the solubility of zaleplon (BCS class II
drug) via micronization technique in order to enhance its oral delivery in orodispersible …

Rapid isolation, reliable characterization, and water solubility improvement of polymethoxyflavones from cold‐pressed mandarin essential oil

M Russo, F Rigano, A Arigò, D Sciarrone… - Journal of …, 2016 - Wiley Online Library
Polymethoxyflavones possess many biological properties, as lipid‐lowering, hypoglycaemic,
anti‐inflammatory, antioxidant, and anticancer activities, therefore, they may be employed as …

[PDF][PDF] Amoxycillin trihydrate floating-bioadhesive drug delivery system for eradication of helicobacter pylori: preparation, in vitro and ex vivo evaluation

N Dudhipala, A Narala, KY Janga, R Bomma - J Bioequiv Availab, 2016 - researchgate.net
The aim of the present investigation was to formulate and evaluate floating-bioadhesive
tablets of amoxicillin trihydrate (ATFBT), to provide local action in the treatment of …

Rapid oral transmucosal delivery of zaleplon–lavender oil utilizing self-nanoemulsifying lyophilized tablets technology: development, optimization and …

SA Ali, NA Alhakamy, KM Hosny, E Alfayez… - Drug Delivery, 2022 - Taylor & Francis
Based on the administration convenience, transmucosal buccal drug delivery allows special
strength points over peroral routes for systemic delivery. It could achieve local or systemic …

[PDF][PDF] Self-Nano emulsifying drug delivery system of ramipril: formulation and in vitro evaluation

K Madhavi, A Shikha, JK Yadav - Int J Pharm Pharm Sci, 2016 - academia.edu
Objective: The primary goal of the present work was to formulate and evaluate self-nano
emulsifying drug delivery systems (SNEDDS) of ramipril in order to improve the solubility of …