Cold atmospheric plasma: a new strategy based primarily on oxidative stress for osteosarcoma therapy

M Mateu-Sanz, J Tornín, MP Ginebra… - Journal of clinical …, 2021 - mdpi.com
Osteosarcoma is the most common primary bone tumor, and its first line of treatment
presents a high failure rate. The 5-year survival for children and teenagers with …

Cold atmospheric plasma in the treatment of osteosarcoma

D Gümbel, S Bekeschus, N Gelbrich, M Napp… - International journal of …, 2017 - mdpi.com
Human osteosarcoma (OS) is the most common primary malignant bone tumor occurring
most commonly in adolescents and young adults. Major improvements in disease-free …

[HTML][HTML] Cold atmospheric plasma enhances doxorubicin selectivity in metastasic bone cancer

M Mateu-Sanz, MP Ginebra, J Tornín… - Free Radical Biology and …, 2022 - Elsevier
High-dose systemic chemotherapy constitutes a main strategy in the management of bone
metastases, employing drugs like doxorubicin (DOX), related with severe side effects. To …

Toxicity and immunogenicity in murine melanoma following exposure to physical plasma‐derived oxidants

S Bekeschus, K Rödder, B Fregin, O Otto… - Oxidative medicine …, 2017 - Wiley Online Library
Metastatic melanoma is an aggressive and deadly disease. Therapeutic advance has been
achieved by antitumor chemo‐and radiotherapy. These modalities involve the generation of …

Cold atmospheric plasma causes a calcium influx in melanoma cells triggering CAP-induced senescence

C Schneider, L Gebhardt, S Arndt, S Karrer… - Scientific reports, 2018 - nature.com
Cold atmospheric plasma (CAP) is a promising approach in anti-cancer therapy, eliminating
cancer cells with high selectivity. However, the molecular mechanisms of CAP action are …

Effects and Mechanisms of Non-Thermal Plasma-Mediated ROS and Its Applications in Animal Husbandry and Biomedicine

Y Yang, Y Wang, S Wei, X Wang, J Zhang - International Journal of …, 2023 - mdpi.com
Non-thermal plasma (NTP) is an ionized gas composed of neutral and charged reactive
species, electric fields, and ultraviolet radiation. NTP presents a relatively low discharge …

Effect of direct plasma treatment and plasma‐treated liquid on cutaneous squamous cell carcinoma: A proof‐of‐concept study

GD Özdemir, UK Ercan, O Karaman… - Plasma Processes and …, 2023 - Wiley Online Library
This study investigates the efficacy of cold atmospheric plasma (CAP) in treating squamous
cell carcinoma (SCC), a highly metastatic cancer. To assess the anticancer activity, two CAP …

Acidification is an essential process of cold atmospheric plasma and promotes the anti-cancer effect on malignant melanoma cells

C Schneider, L Gebhardt, S Arndt, S Karrer… - Cancers, 2019 - mdpi.com
(1) Background: Cold atmospheric plasma (CAP) is ionized gas near room temperature. The
anti-cancer effects of CAP were confirmed for several cancer types and were attributed to …

Cold physical plasma selectively elicits apoptosis in murine pancreatic cancer cells in vitro and in ovo

KR Liedtke, S Diedrich, O Pati, E Freund… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Poor prognosis of pancreatic cancer has remained almost unchanged in
recent years. Cold physical plasma was suggested as an innovative anticancer strategy, but …

[HTML][HTML] Current Status and Future Trends of Cold Atmospheric Plasma as an Oncotherapy

X Dai, J Wu, L Lu, Y Chen - Biomolecules & Therapeutics, 2023 - ncbi.nlm.nih.gov
Cold atmospheric plasma (CAP), a redox modulation tool, is capable of inhibiting a wide
spectrum of cancers and has thus been proposed as an emerging onco-therapy. However …