The European Association for Cardio-Thoracic Surgery (EACTS) established a
multidisciplinary task force of experts involved in perioperative and long-term care of …

Disclaimer 2017: The EACTS Guidelines represent the views of the EACTS and were
produced after careful consideration of the scientific and medical knowledge and the …

Individualized anticoagulation management and improvement of the safety and
effectiveness of oral anticoagulant have always been the focus of clinicians' attention. D …

Background Patients with a mechanical heart valve (MHV) require oral anticoagulation. Poor
anticoagulation control is thought to be associated with adverse outcomes, but data are …

New antithrombotic drugs have been developed, new valve types have been designed and
minimally invasive transcatheter techniques have emerged, making the choice of …

Background Mechanical heart valve replacement (MHVR) is an effective method for the
treatment of severe heart valve disease; however, it subjects patient to lifelong warfarin …

Heart valve replacements are critical for patients with valve malfunctions, and the tri-leaflet
mechanical heart valve (tMHV) is one of the most durable options available. The tMHV is …

Objective Oral anticoagulation with vitamin K antagonists is recommended after mechanical
heart valve replacement. However, data regarding the association between the quality of …

Cardiovascular disease remains one of the major causes of human morbidity and mortality
worldwide. While the past 40 years has brought major progress in cardiac valve repairs and …

Background Patient self-management (PSM) of vitamin K antagonists (VKA) seems a very
promising model of care for oral anticoagulation in terms of efficacy and safety. In …