The dysregulation of the β-cell functional mass, which is a reduction in the number of β-cells
and their ability to secure adequate insulin secretion, represents a key mechanistic factor …

Protein quality control ensures the degradation of damaged and misfolded proteins.
Derangement of proteostasis is a primary cause of aging and age‐associated diseases. The …

Background Hyperuricemia and gout are a group of disorders of purine metabolism. In
recent years, the incidence of hyperuricemia and gout has been increasing, which is a …

(1) Adipsin is an adipokine that may link increased fat mass and adipose tissue dysfunction
to obesity-related cardiometabolic diseases. Here, we investigated whether adipsin serum …

Adipsin is an adipokine predominantly synthesized in adipose tissues and released into
circulation. It is also known as complement factor-D (CFD), acting as the rate-limiting factor …

Adipose tissue secretes many regulatory factors called adipokines. Adipokines affect the
metabolism of lipids and carbohydrates. They also influence the regulation of the immune …

Adult growth hormone deficiency (AGHD) is considered a rare endocrine disorder involving
patients with childhood-onset and adult-onset growth hormone deficiency (AoGHD) and …

In the genesis and progression of cardiovascular and metabolic diseases (CVMDs), adipose
tissue plays a pivotal and dual role. Complement factor D (CFD, also known as adipsin) …

Adipose tissue (AT) adapts to overnutrition in a complex process, wherein specialized
immune cells remove and replace dysfunctional and stressed adipocytes with new fat cells …

Makgeolli, a widely consumed traditional alcoholic beverage in Korea, is brewed mainly
from rice using Nuruk as a fermentation starter, which contains fungi, yeast, and lactic acid …