One of the hallmarks of cancer is angiogenesis, a series of events leading to the formation of
the abnormal vascular network required for tumor growth, development, progression, and …

Doublecortin-like kinase 1 (DCLK1), a protein molecule, has been identified as a tumor stem
cell marker in the cancer cells of gastrointestinal, pancreas, and human colon. DCLK1 …

The existence of adult pancreatic progenitor cells has been debated. While some favor the
concept of facultative progenitors involved in homeostasis and repair, neither a location nor …

Background More than 80% of intestinal neoplasia is associated with the adenomatous
polyposis coli (APC) mutation. Doublecortin-like kinase 1 (Dclk1), a kinase protein, is …

Double cortin‐like kinase 1 (DCLK1) plays important roles during the epithelial‐
mesenchymal transition (EMT) process in human colorectal cancer (CRC). However, the …

Hepatocellular carcinoma (HCC) is the main type of primary liver malignancy and the fourth
leading cause of cancer-related death worldwide. MicroRNAs (miRNAs), a type of non …

Simple Summary Doublecortin-like kinase 1 (DCLK1) is a tumor stem cell marker in colon,
pancreatic, and potentially other cancers that has received wide attention recently. Aside …

Tuft cells are epithelial chemosensory cells with unique morphological and molecular
characteristics, the most noticeable of which is a tuft of long and thick microvilli on their …

CAR-T (chimeric antigen receptor T cells) immunotherapy is effective in many hematological
cancers; however, efficacy in solid tumors is disappointing. Doublecortin-like kinase 1 …

Purpose Metastasis is a primary cause of colorectal cancer (CRC)-related death, and cancer
stem cells (CSCs) are thought to be majorly responsible for initiating metastatic behaviors …