R Khalil, K Al-Mahzoum, M Barakat, M Sallam - Pathogens, 2024 - mdpi.com
Direct-acting antivirals (DAAs) revolutionized the therapeutics of chronic hepatitis C. The emergence and transmission of HCV variants with resistance-associated substitutions …
Background Sofosbuvir, velpatasvir and voxilaprevir (SOF/VEL/VOX) is the recommended rescue therapy for patients with chronic hepatitis C infection who fail direct‐acting antivirals …
Y Xu, L Li, Y Yang, C Huang, H Zou - Talanta, 2024 - Elsevier
Developing a simple, reliable, and sensitive hepatitis C virus (HCV) genetic sensing platform is of great significance for diagnosing diseases and selecting appropriate antiviral …
A Mustafa, S Davlidova, SH Abidi… - BMJ Open …, 2025 - bmjopengastro.bmj.com
Objective The emergence of resistance-associated substitutions (RASs) poses a significant challenge to the effective treatment of hepatitis C virus (HCV) infection using direct-acting …
EE Zelenova, AA Karlsen, DV Avdoshina… - Molecular Biology, 2024 - Springer
The E6 and E7 proteins of the high risk human papillomaviruses (HR HPVs) play a key role in the oncogenesis associated with papillomavirus infection. Data on the variability of these …
Hepatitis C virus (HCV) remains a significant global health challenge. Approximately 50 million people were living with chronic hepatitis C based on the World Health Organization …
NN Hendi, A Mahdi, R AlYafie - 2025 - intechopen.com
Hepatitis poses a major global health challenge due to viral infections that lead to significant liver inflammation and associated morbidity and mortality. Although traditional therapies …
G Morsica, R Vercesi, H Hasson, E Messina… - Viruses, 2021 - mdpi.com
Resistance-associated substitutions (RASs) may exist prior to treatment and contribute to the failure of treatment with direct-acting antivirals (DAAs). As the major site of HCV replication …
Abstract Hepatitis C Virus (HCV) induces liver inflammation, which can develop to liver cirrhosis and hepatocellular carcinoma. In 2021, approximately 58 million people are …