Contemporary Insights into Hepatitis C Virus: A Comprehensive Review

M Sallam, R Khalil - Microorganisms, 2024 - mdpi.com
Hepatitis C virus (HCV) remains a significant global health challenge. Approximately 50
million people were living with chronic hepatitis C based on the World Health Organization …

[HTML][HTML] An Increase in the Prevalence of Clinically Relevant Resistance-Associated Substitutions in Four Direct-Acting Antiviral Regimens: A Study Using GenBank …

R Khalil, K Al-Mahzoum, M Barakat, M Sallam - Pathogens, 2024 - mdpi.com
Direct-acting antivirals (DAAs) revolutionized the therapeutics of chronic hepatitis C. The
emergence and transmission of HCV variants with resistance-associated substitutions …

Real‐life effectiveness of sofosbuvir/velpatasvir/voxilaprevir in hepatitis C patients previously treated with sofosbuvir/velpatasvir or glecaprevir/pibrentasvir

JC Ruiz‐Cobo, J Llaneras, X Forns… - Alimentary …, 2024 - Wiley Online Library
Background Sofosbuvir, velpatasvir and voxilaprevir (SOF/VEL/VOX) is the recommended
rescue therapy for patients with chronic hepatitis C infection who fail direct‐acting antivirals …

Catalytic hairpin assembly triggering amplified DNAzyme-feedback for sensitive detection of hepatitis C virus genotype 1b

Y Xu, L Li, Y Yang, C Huang, H Zou - Talanta, 2024 - Elsevier
Developing a simple, reliable, and sensitive hepatitis C virus (HCV) genetic sensing platform
is of great significance for diagnosing diseases and selecting appropriate antiviral …

Prevalence of resistance-associated substitutions (RAS) in hepatitis C virus in the Former Soviet Union countries

A Mustafa, S Davlidova, SH Abidi… - BMJ Open …, 2025 - bmjopengastro.bmj.com
Objective The emergence of resistance-associated substitutions (RASs) poses a significant
challenge to the effective treatment of hepatitis C virus (HCV) infection using direct-acting …

Amino acid substitution patterns in the E6 and E7 Proteins of HPV type 16: Phylogeography and Evolution

EE Zelenova, AA Karlsen, DV Avdoshina… - Molecular Biology, 2024 - Springer
The E6 and E7 proteins of the high risk human papillomaviruses (HR HPVs) play a key role
in the oncogenesis associated with papillomavirus infection. Data on the variability of these …

[PDF][PDF] Contemporary Insights into Hepatitis C Virus: A Comprehensive Review. Microorganisms 2024, 12, 1035

M Sallam, R Khalil - 2024 - researchgate.net
Hepatitis C virus (HCV) remains a significant global health challenge. Approximately 50
million people were living with chronic hepatitis C based on the World Health Organization …

[HTML][HTML] Advanced Hepatitis Management: Precision Medicine Integration

NN Hendi, A Mahdi, R AlYafie - 2025 - intechopen.com
Hepatitis poses a major global health challenge due to viral infections that lead to significant
liver inflammation and associated morbidity and mortality. Although traditional therapies …

Compartmentalization of Resistance-Associated Substitutions in HIV/HCV-Infected Patients: Possible Correlation with Infecting HCV Genotype

G Morsica, R Vercesi, H Hasson, E Messina… - Viruses, 2021 - mdpi.com
Resistance-associated substitutions (RASs) may exist prior to treatment and contribute to the
failure of treatment with direct-acting antivirals (DAAs). As the major site of HCV replication …

Functional and morphological analysis of hepatitis C virus assembly

S Eu - 2022 - archiv.ub.uni-heidelberg.de
Abstract Hepatitis C Virus (HCV) induces liver inflammation, which can develop to liver
cirrhosis and hepatocellular carcinoma. In 2021, approximately 58 million people are …