Bacteria of the genus Legionella are natural pathogens of amoebae that can cause a severe
pneumonia in humans called Legionnaires' Disease. Human disease results from inhalation …

Endosomes are dynamic intracellular compartments that control the sorting of a constant
stream of different transmembrane cargos either for ESCRT‐mediated degradation or for …

The Commander complex is required for endosomal recycling of diverse transmembrane
cargos and is mutated in Ritscher-Schinzel syndrome. It comprises two sub-assemblies …

Eukaryotic cells traffic proteins and lipids between different compartments using protein-
coated vesicles and tubules. The retromer complex is required to generate cargo-selective …

The tubular endolysosomal network is a quality control system that ensures the proper
delivery of internalized receptors to specific subcellular destinations in order to maintain …

The retromer complex has a well-established role in endosomal protein sorting, being
necessary for maintaining the dynamic localisation of hundreds of membrane proteins that …

Legionella pneumophila grows intracellularly within the membrane-bound Legionella-
containing vacuole (LCV) established by proteins translocated via the bacterial type IV …

Retromer is a master regulator of cargo retrieval from endosomes, which is critical for many
cellular processes including signaling, immunity, neuroprotection, and virus infection. The …

The fate of influenza A virus (IAV) infection in the host cell depends on the balance between
cellular defence mechanisms and viral evasion strategies. To illuminate the landscape of …

The highly conserved retromer complex controls the fate of hundreds of receptors that pass
through the endolysosomal system and is a central regulatory node for diverse metabolic …