Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are elucidated as
cells that can perpetuate themselves via autorestoration. These cells are highly resistant to …

Wilms tumour is the most common renal malignancy of childhood. The disease is curable in
the majority of cases, albeit at considerable cost in terms of late treatment-related effects in …

Blastemal histology in chemotherapy-treated pediatric Wilms tumors (nephroblastoma) is
associated with adverse prognosis. To uncover the underlying tumor biology and find …

In Europe, almost 1000 children are diagnosed with a malignant renal tumour each year.
The vast majority of cases are nephroblastoma, also known as Wilms' tumour (WT). Most …

Wilms Tumor, the most common pediatric kidney cancer, evolves from the failure of terminal
differentiation of the embryonic kidney. Here we show that overexpression of the …

Wilms' tumor, or nephroblastoma, is the most common pediatric renal cancer. The tumors
morphologically resemble embryonic kidneys with a disrupted architecture and are …

MicroRNAs (miRNAs) are involved in virtually all biological processes, including stem cell
maintenance, differentiation, and development. The dysregulation of miRNAs is associated …

Identification of tissue‐specific renal stem/progenitor cells with nephrogenic potential is a
critical step in developing cell‐based therapies for renal disease. In the human kidney …

The adult mammalian kidney is a poorly regenerating organ that lacks the stem cells that
could replenish functional homeostasis similarly to, eg, skin or the hematopoietic system …

Renal cell carcinoma (RCC) is a common form of urologic tumor that originates from the
highly heterogeneous epithelium of renal tubules. Over the last decade, targeting therapies …