Recombinant ASF live attenuated virus strains as experimental vaccine candidates

DP Gladue, MV Borca - Viruses, 2022 - mdpi.com
African swine fever (ASF) is causing a pandemic affecting swine in a large geographical
area of the Eastern Hemisphere, from Central Europe to East and Southeast Asia, and …

Deletion of the A137R gene from the pandemic strain of African swine fever virus attenuates the strain and offers protection against the virulent pandemic virus

DP Gladue, E Ramirez-Medina, E Vuono… - Journal of …, 2021 - Am Soc Microbiol
African swine fever virus (ASFV) is causing a devastating pandemic in domestic and wild
swine within an extended geographical area from Central Europe to East Asia, resulting in …

Attenuated African swine fever viruses and the live vaccine candidates: a comprehensive review

J Fan, H Yu, F Miao, J Ke, R Hu - Microbiology Spectrum, 2024 - journals.asm.org
The African swine fever virus (ASFV) is spreading worldwide and causing huge economic
losses to the global pig industry. The ASFV genome is 170–193 kb in length, contains …

African swine fever virus and host response: transcriptome profiling of the Georgia 2007/1 strain and porcine macrophages

G Cackett, R Portugal, D Matelska, L Dixon… - Journal of …, 2022 - Am Soc Microbiol
African swine fever virus (ASFV) has a major global economic impact. With a case fatality in
domestic pigs approaching 100%, it currently presents the largest threat to animal farming …

Evaluation of the deletion of MGF110-5L-6L on swine virulence from the pandemic strain of African swine fever virus and use as a DIVA marker in vaccine candidate …

E Ramirez-Medina, E Vuono, E Silva, A Rai… - Journal of …, 2022 - Am Soc Microbiol
African swine fever virus (ASFV) is responsible for an ongoing pandemic that is affecting
central Europe, Asia, and recently the Dominican Republic, the first report of the disease in …

The 2022 Outbreaks of African Swine Fever Virus Demonstrate the First Report of Genotype II in Ghana

E Spinard, A Rai, J Osei-Bonsu, V O'Donnell… - Viruses, 2023 - mdpi.com
African swine fever (ASF) is a lethal disease of domestic pigs that has been causing
outbreaks for over a century in Africa ever since its first discovery in 1921. Since 1957, there …

Deletion of African swine fever virus histone-like protein, A104R from the Georgia isolate drastically reduces virus virulence in domestic pigs

E Ramirez-Medina, EA Vuono, S Pruitt, A Rai… - Viruses, 2022 - mdpi.com
African swine fever virus (ASFV) is the etiological agent of a frequently lethal disease, ASF,
affecting domestic and wild swine. Currently, ASF is causing a pandemic affecting pig …

Deletion of the H240R Gene in African Swine Fever Virus Partially Reduces Virus Virulence in Swine

E Ramirez-Medina, A Rai, N Espinoza, A Valladares… - Viruses, 2023 - mdpi.com
African swine fever (ASF) is a highly contagious disease that affects wild and domestic
swine. Currently, the disease is present as a pandemic affecting pork production in Eurasia …

Evaluation of the Function of the ASFV KP177R Gene, Encoding for Structural Protein p22, in the Process of Virus Replication and in Swine Virulence

EA Vuono, E Ramirez-Medina, S Pruitt, A Rai… - Viruses, 2021 - mdpi.com
African swine fever virus (ASFV) causes a devastating disease of swine that has caused
outbreaks in Central Europe since 2007, spreading into Asia in 2018. ASFV is a large …

African swine fever virus MGF110-7L induces host cell translation suppression and stress granule formation by activating the PERK/PKR-eIF2α pathway

H Zhong, S Fan, Y Du, Y Zhang, A Zhang… - Microbiology …, 2022 - Am Soc Microbiol
African swine fever (ASF) is a highly contagious and often lethal disease of pigs caused by
ASF virus (ASFV) and recognized as the biggest killer in global swine industry. Despite …